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Flashcards in ADHD - Segars Deck (21):
1

Function of STIMULANTS for ADHD

Enhance NE/DA/5-HT transmission via interfering with pre-synaptic reuptake by VMAT --> increased NT release

2

Stimulant drugs for ADHD

Amphetamine
Dextroamphetamine
Lisdexamphetamine
Methamphetamine
Methylphenidate
Dexmethylphenidate

3

**ADHD Stimulant drugs - FDA regulations?

- 1 month supply
- No refills
- No samples

4

Side effects of amphetamine stimulants for ADHD

- Decreased appetite
- Insomnia
- HA, abdominal pain
- Irritability, aggression
- Elevated BP/HR -- stroke, MI

5

Non-stimulant meds for ADHD

- Atomoxetine
- Guanfacine
- Clonidine

6

Function of NON-stimulants for ADHD

Enhance NT transmission via inhibiting re-uptake (Atomoxetine) of NE or activating CNS alpha-2 receptors (Guanfacine, Clonidine)

7

**Onset of activity for stimulants vs. non-stimulants


**Who is given the non-stimulant drugs for ADHD?

**Regulations on non-stimulant drugs for ADHD?

Stimulants = 24 hours
Non = 2-4 weeks

Intolerance to stimulants or parent resistance to stimulants

NONE (not controlled)

8

Can non-stimulants be broken up and put in/on food?

NO

9

Different side effects of non-stimulants compared to stimulants?

- HYPOtension
- Dizziness
- Sedation/somnolence

10

Adderall
- Form?
- Drug(s)?
- Age?
- Percentage of each? (XR)

Pill

d,l-amphetamine, dextroamphetamine

3+

XR = 50/50

11

Dexedrine
- Form?
- Drug(s)?
- Age?

Spansules (capsule that releases drug over time)

Dextroamphetamine

3+

12

Vyvanse
- Form?
- Drug(s)?
- Age?

Pill

Lisdexamfetamine (pro-drug of dextroamphetamine)

6+

13

Concerta
- Form?
- Drug(s)?
- IR or DR?
- Percentage of each? (XR)
- Age?

Pill

d,l-methylphenidate

BOTH (2 phases)

22% immediate (outer coat), 78% delayed

6+

14

Ritalin
- Form?
- Drug?
- IR or DR?
- Percentage of each? (XR)
- Age?

Pill

d,l-methylphenidate

BOTH

50/50

6+

15

Metadate
- Form?
- Drug(s)?
- IR or XR?
- Percentage of each? (XR)
- Age?

Pill

d,l-methylphenidate

BOTH

30/70

6+

16

Aptensio
- Form?
- Drug(s)?
- IR or XR?
- Percentage of each? (XR)
- Age?

Pill

d,l-methylphenidate

BOTH

40/60

6+

17

Daytrana
- Form?
- Drug(s)?
- Location? For how long?
- Onset?
- Age?

**PATCH

d,l, methylphenidate

Hip - 9 hours (for 12 hours of action)

1-2 hours

6+

18

Quillivant
- Form?
- Drug(s)?
- IR or XR?
- Percentage of each? (XR)
- Age?

Extended-release ORAL SUSPENSION (powder)

d-methylphenidate

BOTH

20/80

6+

19

QuilliChew - how is it different than Quillivant?

Extended-release CHEWABLE TABLET

20

Focalin
- Form?
- Drug(s)?
- IR or XR?
- Percentage of each?
- Age?

Pill

Dexmethylphenidate

BOTH

50/50

6+

21

Approved age for non-stimulant drugs?

6+