ADRENAL GLANDS

Question 1

in CAH whats the main deficiency

Answer 1

cortisol

Question 2

what can you use as a diagnosis for 21 alpha hydroxyls deficiency

Answer 2

17 alpha hydroxylase as this is the product that is supposed to be converted by the enzyme

Question 3

labs

Answer 3

hypekalaemia
hyponatremia
hypoglycaemia

Question 4

zones of adrenal gland

Answer 4

Z. Glomerulosa- aldosterone, z. Fasiculata (cortisol ) z. Reticularis (Testosterone)

Question 5

why are the kidneys enlarged

Answer 5

compensation as more ACTH is produced to get more cortisol

Question 6

types of classic (95%)

Answer 6

Two types are classic forms, known as the salt-wasting and simple virilizing types(will have no salt wasting) .

Question 7

who suffers from infertility in CAH

Answer 7

BOTH men and women as high levels of testerosteone can cause infertility in men Think steroids!

Question 8

those with aldosterone impairment too

Answer 8

Those with hypoaldosteronism – fludrocortisone replacement required

Question 9

whats the acid base status in these patients

Answer 9

METABOLIC ACIDOSIS (hyperkalemia)

Question 10

classic - both salt wasting and simple virilisisn

Answer 10

in which forms will females have ambiguous