Adrenergic Antagonists

Question 1

non selective alpha blockers

Answer 1

phenoxybenzamine

phentolamine

Question 2

blocks A1 and A2 causing increase of NE that then stimulates beta receptors
treatment for HTN in pheochromocytoma

Answer 2

phenoxybenzamine

Question 3

block A1 and A2 causing reflex stimulation of SANS due to hypotension cause tachycardia
used to treat pheochromocytoma

Answer 3

phentolamine

Question 4

selective A1 blockers

Answer 4

prazosin
terazosin
doxazosin
tamsulosin

Question 5

A1a inactivation: relaxation of bladder trigone, prostate, urethra - increase urinary outflow, complete emptying of bladder

Answer 5

selective A1 blockers

Question 6

used to treat essential HTN

Answer 6

prazosin
terazosin
doxazosin

Question 7

patient loses consciousness 30-60 minutes after 1st dose > result severe postural hypotension > avoid driving and hazardous activity. admin initial dose at bed time

Answer 7

1st dose effect

Question 8

used to treat BPH and given with finasteride

Answer 8

tamsulosin

Question 9

selective A2 blcokers

Answer 9

yohimbine

mirtazapine

Question 10

increase NE
aphrodisiac
SE: HTN

Answer 10

yohimbine

Question 11

increase NE
depression
SE: increase NE at synaptic cleft in CNS

Answer 11

mirtazapine

Question 12

non selective beta blockers

Answer 12

propranolol
sotalol
timolol
carteolol with ISA
nadolol
penbutolol with ISA
pindolol with ISA

Question 13

decreases HR, CO, renin, insulin, aqueous humor secretion

causes vasoconstriction and fall in BP

Answer 13

propranolol

Question 14

used to treat HTN, angina cardiac arrhythmias, CHF, MI, used to depress sympathetic - essential tremors, hyperthyroidism, stage fright, migraine and glaucome

Answer 14

propranolol

Question 15

antidote for beta blockers overdose increase AC - increase cAMP; has inotropic and chronotropic effects o heart

Answer 15

glucagon

Question 16

K blocker, prevents re polarization, prolongs potentials

Answer 16

sotalol

Question 17

used to treat glaucoma

dont give to diabetics

Answer 17

timolol

Question 18

selective cardio B1 blockers

Answer 18

betaxolol
bisoprolol
esmolol
atenolol
metoprolol
acebutolol with ISA
nebivolol

Question 19

alpha and beta blockers

Answer 19

carvedilol

labetalol with ISA

Question 20

drug of choice with HTN emergency

Answer 20

labetalol