advanced higher biology proteomics and protein structure Flashcards
0
Q
Why is the proteome larger than the genome?
A
- in RNA splicing different sequences can be considered as exons or introns thus many proteins can be produced from one DNA strand
- in post-translational modification, proteins can be altered by addition of chemical groups or the covalent cleavage of the polypeptide thus increasing the range of proteins that can be created
1
Q
The proteome
A
The entire set of proteins expressed by a genome
2
Q
Post-translational modification occurs in: (3)
A
The Golgi apparatus, endoplasmic reticulum and target site of the protein
3
Q
Post-translational addition of chemical groups examples
A
Phosphorylation, acylation and alkylation
4
Q
Post-translational covalent cleavage examples
A
Proteases and autocatalytic cleavage
5
Q
Intracellular proteins
A
Lyzozymes found in lysosomes
6
Q
Membrane-bound proteins
A
Intrinsic and extrinsic proteins
7
Q
Extracellular proteins
A
Insulin and digestive enzymes
