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Pharmacology 2 > Adverse > Flashcards

Adverse Flashcards

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1
Q

H2 antagonists

A

GI, CNS
HypoT, arrhythmias

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2
Q

Antacids

A

Rebound acidity
Alkalosis
Constipation, diarrhea
HyperCa, hypophosphatemia

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3
Q

PPIs

A

CNS, GI
Upper respiratory: cough, stuffy, hoarse, epistaxis (nosebleed)

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4
Q

GI protectant

A

GI, CNS
Dry mouth

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5
Q

Prostaglandin

A

Mainly GI
GU (increased bleed, irregular menses)
Causes abortions

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6
Q

Digestive enzymes

A

GI
Abnormal electrolytes

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7
Q

Chemical stimulants

A

GI, CNS
Sweat, palpitations, flushing, fainting
Cathartic dependence
(Castor oil) blocks fat soluble vitamin absorption

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8
Q

Bulk stimulants

A

GI, CNS
Sweat, palpitations, flushing, fainting

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9
Q

Osmotic laxatives

A

GI, CNS
Sweat, palpitations, flushing, fainting
Dehydration, dry mouth

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10
Q

Lubricants

A

GI, CNS
Sweat, palpitations, flushing, fainting
(Mineral oil) leakage and staining

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11
Q

GI stimulants

A

GI
CV (decreased BP and HR)
Weakness, fatigue

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12
Q

Antidiarrheal

A

GI
Fatigue, weak, dizzy

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13
Q

Phenothiazines

A

CNS, photophobia
CV: hypoT, hyperT, arrhythmia
GU: menstrual disorders, galactorrhea (milk), gynecomastia (swelling)

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14
Q

Nonphenothiazines

A

CNS
Extrapyramidal (involuntary movements): dystonia (spasms), akathisia (restless), dyskinesia (jerky movements), parkinsonism (slowness and rigidity)

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15
Q

5-HT3 Receptor Blockers

A

HA, dizzy,
myalgia (muscle pain),
constipation

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16
Q

Substance P/Neurokinin 1 receptor antagonists

A

Anorexia, constipation, diarrhea,
increased liver enzymes,
dehydration, fatigue

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17
Q

Interferons

A

Most common: lethargy, myalgia, arthralgia
Nausea
HA, dizzy
Anorexia
Bone marrow depression

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18
Q

Interleukins

A

Most common: flu like symptoms (lethargy, myalgia, arthralgia, fatigue, fever)
Respiratory difficulties, depression with suicidal thoughts

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19
Q

Colony stimulating factors

A

Most common: generalized pain and bone pain
GI
HA, fatigue, weakness
Alopecia
Dermatitis (eczema)

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20
Q

Immune modulators

A

Unknown

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21
Q

T and B suppressors

A

Increased risk of infection
Increased risk of neoplasm (tumor)
Hepatotoxicity
Renal toxicity and dysfunction
Pulmonary edema

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22
Q

Interleukin antagonist

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A

Nausea, diarrhea
HA
Sinusitis

23
Q

Monoclonal antibody

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A

Flu like
Pulmonary edema
Fluid retention

24
Q

Salicylates

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A

Stomach and clotting
Do not use for fever for kids- Reye Syndrome

25
NSAID
GI, GI pain and bleed Dyspepsia (indigestion) Somnolence (drowsy), dizzy Platelet inhibition HTN Bone marrow suppression with chronic use
26
Acetaminophen
HA Fever Rash Anemia Renal dysfunction Hepatotoxic with OD and chronic use
27
Gold compounds
Stomatitis/glossitis/gingivitis Bone marrow depression Dermatitis Interstitial pneumonia Anaphylactic shock
28
TNF blockers
Risk of fatal infection and development of lymphoma and cancer
29
Glucocorticoid
Increase glucose Lots: GI, CNS, HF, fluid retention, osteoporosis, frail skin that won’t heal quickly Cushing Impaired child growth
30
Mineralocorticoids
Increase fluid volumes HypoK
31
Antitussives
Dries mucous membranes CNS drowsy, HA, dizzy GI nausea, constipation
32
Topical nasal decongestant
Sting and burn Rebound congestion SNS effects
33
Oral decongestants
Rebound congestion SNS effects
34
Topical nasal steroid decongestants
Burn and sting Dry mucous membranes HA Decreased healing
35
Antihistamines
CNS drowsy Anticholinergic dry, nausea, urine hesitation CV arrhythmia
36
Expectorants
GI CNS HA and dizzy Rash Masking
37
Mucolytics
GI Stomatitis Rhinorrhea (runny nose) Bronchospasm Rash at nebulizer area
38
Xanthines
GI Irritated Tachycardia Hyperglycemia Seizure Brain damage and death
39
Sympathomimetics
SNS CNS GI Bronchospasm Cardiac - arrhythmia, hypertension, sweat, pallor, flushing
40
Anticholinergic
Can’t see spit poop pee CNS dizzy, HA, nervous, fatigue, sore throat, retention, palpitations
41
Inhaled steroids
Sore throat, hoarseness, coughing Dry mouth, throat infections
42
Leukotriene receptor antagonists
URI, pharyngitis, cough CNS dizzy and HA GI and increased liver enzymes Pain, fever, myalgia Grouchy kids
43
Lung surfactants
Unknown
44
Nitrates
Related to vasodilation and decreased blood flow 2 biggies: Hypotension and HA Also GI, flush, pallor, sweat
45
Beta blockers
Related to SNS blocking Hypotension and bradycardia GI CNS dizzy, fatigue, depression CV CHF, decreased CO, arrhythmia Respiratory- bronchospasm, dyspnea, cough
46
Calcium channel blockers
Most common: hypotension, arrhythmia GI Skin HA
47
Cardiac glycosides
CNS HA, weak, drowsy, yellow halo GI anorexia Brady arrhythmias
48
Phosphodiesterase inhibitors
Most common: arrhythmias, hypotension, GI, thrombocytopenia (reduced platelets)
49
HCN channel blockers
Biggest one: bradycardia HyperT, atrial fibrillation, luminous phenomena (sudden vision changes)
50
Class 1
CNS dizzy and fatigue (common), slurred GI nausea and vomiting CV arrhythmia (common) Respiratory depression Rash, hair loss, potential bone marrow suppression
51
Class 2
Related to SNS block CNS dizzy, insomnia, dream, fatigue (common) CV hypotension and bradycardia (common), AV block, arrhythmia Respiratory bronchospasm and dyspnea GI nausea, vomiting, anorexia Decreased libido and exercise tolerance Altered blood glucose
52
Class 3
GI nausea and vomiting CNS weak and dizzy CV arrhythmia
53
Class 4
Common: dizzy, weak, fatigue Depression GI HypoT, CHF, shock

Pharmacology 2 (5 decks)

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