adverse drug Flashcards Preview

Derm > adverse drug > Flashcards

Flashcards in adverse drug Deck (17)
Loading flashcards...
1

most common type of drug eruption

exanthem or morbillaform rash

2

5 causes of uticaria

bugs, drugs, stress, food, ideopathic ( 85%)

3

differences in Uticaria from angioedema

AE occurs in mucosal surfaces of the mouth, lasts 2-3 day, painful

4

what does lesiosn on Erythema Multiforme llook like

target--- syphalis immitates

5

pathology of EM

autoimmune reaction of skin --- does not progress like TEN

6

treatment of EM

antihistamines, corticosteroids

7

SJS s/sx

sever widespread mucsal involvement along epidermal detachment -- nikosky sign, skin hurts, occurs 7-21 days after drug started

8

TEN S/Sx

same as SJS just widespread greater than 30 BSA -- acute onset of bullae and sloughing skin

9

Exfoliative Erythrodema

Red man syndrome-- Diffuse erythema followed scalin g of skin

10

whast DRESS

Drug Rash with Eosinophilia and Sytemic Symptoms - severe skin rx with systemic symptoms--- commonly form anticonvulsants and sulfonamides

11

DRESS sx /s

2-6 weeks after drug started--- facial edema--- liver problems kill most-- tx is long term corticosteroids

12

fixed drug eruption

dusky or red macules then into plaques or bullae

13

common cause of FDR and tx

sulfa, NSaids, barbituates, tetracyclein,
topical steroids

14

immune complexes deposited in post capillary venules with palpable purpura

vasculitits

15

Vasculits sx and s

pin head size reddish puntae with cayeene pepper grain appeareance-- not itchy-- benign

16

sx s of phototoxicity

bad sun burn with hyper pigmentation-- caused by UVR waves

17

tx of phototoxicity

topicla steroids, sunscren, drug witdrwaal