Adverse reactions Flashcards
(15 cards)
Penicillins
Anaphylaxis
Amoxicillin
Superinfection
Cephalexin (1st gen)
diarrhea
Cefaxlor (2nd gen)
Superinfection
DDI: enhancement of warfarin
Cephlosporins major warning
DO NOT GIVE TO PATIENTS WITH PENICILLIN ALLERGY
Ceftriaxone
Superinfection
Vancomycin
Ototoxicity, renal toxicity, routine monitoring of plasma levels required
Macrolides
GI disturbances, DD interaction due to P450 (but not Azithromycin)
Tetracyclines
Abnormal bone development, Avoid in pregnancy, fungal superinfection, DD interactions with cations in stomach
Clindamycin
Severe diarrhea, pseudomembranous colitis
Aminoglycosides
Vestibular and auditory toxicity, nephrotoxicity, routine monitoring of plasma levels
Chloramphenicol
bone marrow toxicity, gray baby syndrome
Fluorquinolones
superinfections, DDI with theophylline and antacids, arthropaties
Metronidazole
Antabuse (aldehyde) reaction, candidal superinfection
Sulfonamides
hypersensitivity skin reactions