Bacteria Pathology

Question 1

Streptococcus pyogenes

Answer 1

Pharyngitis, Post-strep sequelae

M-protein: kills PMNs and enhances adherence

Question 2

“Viridans” Streptococci

Answer 2

Endocarditis

Dextrans - enhance adherence to damaged heart valves and teeth

Question 3

Staphlococcus aureus (MSSA, MRSA)

Answer 3

Cutaneous infection, pneumonia, bacteremia, device associated infections

Coagulase - formation of fibrin capsule. Alphatoxin - cytotoxic agent

Question 4

Enterococci (faecium/faecalis)

Answer 4

Bacteremia, intraabdominal infections, UTIs

Question 5

Neisseria gonorrheae

Answer 5

Gonorrhea

Antigenically distinct pili allow for repeat infection

Question 6

Neisseria meningitis

Answer 6

Meningitis

Question 7

E. coli

Answer 7

UTIs, intraabdominal infections, lower respiratory infections, bacteremia, traveler’s diarrhea

Question 8

Pseudomonas aeruginosa

Answer 8

nosocomial (hospital acquired) infections at any site (UTIs, pneumonia)

Question 9

C. diff

Answer 9

Pseudomembranous colitis

Toxins that transfer glucose from UDP-glucose to Rho family GTPases

Question 10

Bacteroides fragalis

Answer 10

intraabdominal and brain abscess

Aerotolerance, superoxides

Question 11

Chlamydia

Answer 11

trachoma, community-acquired pneumonia, urethritis

Elementary bodies infect cells and become reticulate bodies which grow in vaccules and lyse the cell

Question 12

Mycoplasma pneumonia

Answer 12

Community acquired pneumonia

hydrogen peroxide and superoxide radicals

Question 13

Streptococcus pneumoniae

Answer 13

Pneumonia, otitis media, sinusitis

Antiphagocytic capsule