African swine fever Flashcards

1
Q

Virus

A

Asfaviridae

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2
Q

Kenmerken

A
  • complex virus
  • bevat meer dan 50 eiwitten (inclusief structurele)
  • door virussen gecodeerde enzymen
    > transcriptie
    > post translationele modificatie mRNA
  • vrius afgeven door budding en na cellulaire desintegratie
    -stabiel in omgeving breed scala temp (4-20°C), pH
  • heel lang overleven in vlees
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3
Q

Vernietiging door

A
  • Verhitting
  • behandeling lipideoplosmiddelen
  • ontsmettingsmiddelen zoals formaline en halogeenverbindingen
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4
Q

Symptomen

A
1) Hemorragische koorts
> koorts
> anorexie 
> bloedingen overal (oren, neus, huid) 
> abortus
> cyanose
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5
Q

Immuniteit

A

Infecteert Macrofagen en cytotoxische T-cellen krijgen het niet onder controle

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6
Q

Pathogenese

A

1) Oronasale opname
2) xx nasofaryngeale holte
3) Viremie in macro’s
4) ganse lichaam in macrofagen (bv lymfeknopen, placenta, veneus –> bloedingen en sterfte)

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