AIOD Flashcards

1
Q

What are symptoms of AI dz?

A

Claudication (calf, thigh, butt)
embolism (saddle or blue toe syndrome)
Erectile dysfunction

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2
Q

What collateral network supplies distal to AI dz?
why are the collaterals important?

A

lumbar and hypogastric feeding vessles connect to circumflex iliac, hypogastric, femoral and profunda recipients

in extreme, IMA to inferior epigastric and
SMA to IMA and
hemorrhoidal artery via arc of Riolan and meadering mesenteric artery

prevent CLI, main presentation in claudication

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3
Q

What are signs and symptoms of blue toe syndrome?

A

palpable pulses with patchy ischemia (livedo) but distal gangrene can occur

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4
Q

What is Leriche syndrome?

A

Terminal aortic occlusion
Thigh, hip, buttock claudication, atrophy of leg muscles, impotence, decreased femoral pulses

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5
Q

What is small aortic syndrome or hypoplastic aortic syndrome?
What is life expectancy?
Where is plaque?

A

Isolated AI in usually younger females, usually smokers
normal
posterior plaque prox or at bifurcation

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6
Q

What are pullback pressure in AI?

A

Pull back pressure 5-10mmhg at rest or change in systolic pressure greater then 15% indicates dz warranting revasc

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7
Q

What are indications for surgery?

A

disabling claudication
tissue loss
ischemic rest pain

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8
Q

What is natural history of claudicants in AI?

A

1%/year limb loss
5%/year mortality
20-30% require OR in 5 years

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9
Q

What % of AI have CAD?

A

nearly 50%

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10
Q

What are repair techniques for AI?

A

endarterectomy
Aorto-bifem
Fem-Fem
Ax-fem
Obturator bypass
throaci/supra-celiac- fem bypass

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11
Q

When is endarterectomy best suited?

A

Small arteries
Want to avoid prosthetic graft
Erectile dysfunction as may improved hypogastric perfusion
Best for focal stenosis otherwise not usually done

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12
Q

Advantages to End-end in aortobifem?

A

Possible better hemodynamics, less flow turbulence
Less rate of pseudoaneurysm
Close peritoneum over graft
With concomitant aneurismal disease should to end-end

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13
Q

Advantages to end-side in aortobifem?

A

Preserve IMA
Preserve flow hypogastrics
Less erectile dysfunction, paraplegia secondary to cauda equina syndrome
Good if heavily calcified aorta

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14
Q

What is cauda equina?
what are symptoms?

A

damage to the cauda equina causes acute loss of function of the lumbar plexus, (nerve roots) of the spinal canal below the termination of the spinal cord. CES is a lower motor neuron lesion.

Urinary retention
decreased anal tone and consequent fecal incontinence;
sexual dysfunction;
saddle anesthesia;
bilateral (or unilateral) sciatic leg pain and weakness;
and absence of ankle reflex.

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15
Q

What dose of heparin do you give before clamping?
target ACT?

A

70-100units/kg
250-350 secs

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16
Q

Is there benefit of adjunctive profundoplasty in aortobifem?

A

May Improve long-term patency in AI bypasses
5year patency 88%

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17
Q

Advantages/disadvantages for external iliac anastomosis in AI bypass?

A

Good for hostile groin, obese, DM with intertriginous rash
More technically difficult and possible lower patency rates then to fem

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18
Q

when to consider inflow and outflow bypass?

A

tissue loss (appears no increase m&m)

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19
Q

how many patients have improvement of symptoms after ABF for AI?

A

80%
2/3 still have symptoms

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20
Q

When do you do concomittant SMA or Renal bypass?
what is mortality with ABF and ABF with SMA/renal recons?
what is symptom response rate?

A

If associated with the lesion repair
If thought to have reaversible on refractory hypertension or ischemic nephropathy

mortality 1-2% 5-6%(renal/SMA).

Favorable response to HTN 60-70%,
improvement in renal function 30%

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21
Q

what is 5 year patency for endart and ABFG in AI?
10 year patency?
moratlity rates?
10 survival?

A

95% and 85-90%
85-90% and 75-85% (older 95%, but <50yo 66%)
1%, 1-4%
isolated normal life expectency, multilevel disease 50%

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22
Q

patency difference between trans vs retro approach ABF?
PTFE vs Dacron

A

No
No

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23
Q

What are early complications and percentages ABF?

A

Sexual dysfunction <5%
bowl ischemia 2%
MI 1-5%
death 1-4%
ALI 1-3%
bleeding 1-2%

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24
Q

where is bowel ischemia usually found after Bypass for AI?
how to avoid?

A

recto-sigmoid
preserve IMA, keep up perfusion

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25
what are features of neurogenic claudication?
diffues deep aching,burning possible paresthesias from buttock to feet. relieved by sitting or beding over while walking. occurs with walking
26
What are common causes of IC?
SFA stenosis, athersclerosis, pop entrapment, ACD, chronic compartement syndrom, arteriris, thrombosis, FMD, coarctation
27
what are RF for claudication?
HTN, DM, metabolic syndrome, smoking, male, age, DLP, hyperhomocystenemia
28
What is natural history of IC?
10% deteriorate within one year then 2-3% per year to CLI 1% risk of major amputation per year 2-5% risk of cardiac death per year 70% angioplasty rates for 5 years
29
What is the natural history for CLI patients?
30% will lose leg in one year if unconstructable 40% limb loss at 6 months 25% dead in one year 25% CLI resolved
30
What is included in hypercoag workup?
thrombin/prothrombin times activated partial thromboplastin time protein S, protein C assays factove V leidan asay lupus anticoagulant assay heparin induced plt antibodies fibrinogen, plasminogen levels ATIII activity anticardiolipin antibody assay
31
How does hyperhomocysteine cause athero?
high level toxic to endothelium and reduce NO release, promote mSMC proliferation and arterial wall inflammation leading to athero
32
What is risk of surgery for PAD?
5% risk MI, CHF, death
33
What test to perfomr if has IC but palpable pulses?
exercise stress test ABI at rest then walks 3.5km/hr on treadmill with 12% incline if \>20% decrease in ankle pressure for \>3 minutes indicates vascular dz
34
What is the rutherford classification?
0 asympto normal 1 mild claudication completes treadmill test, but ankle pressure \>50mmhg but at least 20mmhg lower then resting value 2 moderate caludication b/w catergories 1 and 3 3 severe claudication cannot complete standard teradmill exercise. AP after exercise \<30 4 rest pain 5 ulcerations not exceeding digits 6 major tissue loss
35
what are features of a walking exercise for PAD?
treadmill or track walking, 35 mins porgressing to 50mins 35 times per week. treadmill incline should elicits IC within 3-5 mins
36
What drugs have evidence in IC?
cilostazol naftidrofuryl statin (supporting evidence)
37
what is cilastozol? what is the evidence
phosphodeisterase inhibitor RCT, 50% increase in walking distance imporve QoL CI in CHF 15% AE
38
What is the evidence for pentoxifylline?
MA questionable benefit
39
What was the BASIL trial? what were findings of the trial?
RCT, angio vs open for severe limb ischemia AFS primary end point at 2 years surivival and AFS better in surgical arm, no difference at six months if patient life expectancy \>2 years then open if attempt endo first then durability of subsequent open worse
40
What is the mortality with LE bypass? wha are some complications?
2% graft stenosis 20% in 1 year major amp 5-10% graft infection 1-3%
41
What are some scoring models for survival with LE intervention?
LEGES Finnvasc Prevent III Basil
42
What are some indications for extra-anatomic bypass?
high-risk laparotomy hostile abdo infected graft AE fistula groin sepsis
43
When is axem or fem-fem best suited? when is obturator bypass best suited?
no endo option, high risk lap, hostile abdo or acute presentation hostile groins
44
what is better unilat ilio fem or fem-fem for patency? what about aorta-fem vs ilio fem?
unilat ilio-fem at ten years no difference at ten years
45
where is fem-fem tunneled?
prefascial plane pre-peritoneal if thin or too fat, previsou surgery, radiation damage to skin
46
What is the mortality periop, 3 yr survival, 5 yr patency for fem-fem?
\<5% 70% 65%
47
What features on duplex are concerning for graft failure?
peak systolic \>300cm/sec inflow or \<60cm/sec midgraft
48
What size better for fem-fem? what amterial?
no difference
49
what % have steal with fem-fem
3% 45% exercise induced
50
Which side axillary artery to choose for ax-fem?
consider non-dominant if will need future left chest surgery if 10mmhg discrepency
51
what is 3 year survival for ax-fem? 5 year patency? 3 yr limb salvage
35% 75% better in claudicants then CLI 70%
52
What is normal resting flow in ax fem? what flow indicates impending graft failure?
600-900 ml/min 300-400 ml.min each limb \<240ml.min in 6mm
53
describe obturator bypass?
``` donor artery exposed retroperitoneal via oblique lower quadrant incision (or trasnperitoneal) dissect medial to external iliac vein and posterior to pubic ramus obturator nerve (may injure) and artery perforate postolaterally membrane must be opened sharply ```
54
What are the 3 and 5 yr patency for obturator bypass?
75 and 60%
55
What does the obturator nerve innervate?
sensory to medial thigh motor of adductor muscles of LE
56
What are features of throaco-fem surgery?
7-8th rib incision tunnel graft retroperitoneally behind or anterior to kidney
57
What are TASC A lesions for AI?
ui/bilat CIA uni/bilat short \<3cm EIA
58
Waht are TASC B lesions for AI?
short infrarenal aorta uni CIA occlusion single or multiple (3-10 cm) isolated EIA uni isolated EIA occlusion
59
What are TASC C lesions for AI?
bilat CIA occlusion bilat isolated EIA stenosis (3-10cm) unilat EIA stenosis into CFA unilat EIA occlusion origin of CFA or iliac heavily calcified uni EIA
60
What are type D TASC lesions for AI?
infrarenal aortic occlusion diffuse aort-iliac dz diffuse stenosis of uni CIA, EIA, and CFA bilat occlusion of EIA iliac leasion in AAA that requires open surgery
61
When should you consider preventative measure for constrast enduced nephropathy? what are they?
GFR \<45ml/min if IV volume bicarb to alkalinize urine (MA shows benefit) metformin can increase risk of AKI
62
What is a significant pullback gradient?
10mmhg \>15% with papaverine
63
what are re-entry devices?
outback pioneer
64
What are mechanical properties of balloon expandable vs self-expanding stents?
balloon better precision high radio-opacity high hoop strength less flexible, premanently defromed, can become dislodged from balloon self-expanding greater felxibility
65
what is the difference between selective stenting and angioplasty in AI?
RCT no difference with selective placement 20% will get stent reintervention and 20% in plasty alone will get reintervention MA better patency with primary stenting reduces long term failure by 40% then plasty alone
66
What are patency rates for TASC lesions for endo in AI dz? for open?
10 yr A or B 70% 5 yr C or D 70% 5 yr 80% patency with 30% comps
67
What are predictors of endovascular failure for AI dz? what can improve patency?
EI dz (PPR 1 year 50%) female RI CLI covered grafts
68
What is the definition of CLI?
persistent, recurring ischemic rest pain requiring opiate \>2 weeks AP \<50mmhg
69
What size vein for LE bypass?
3mm
70
whats a linton patch?
when bypass comes of CFA endart anastomoses
71
what is the patency of isolated popliteal target?
situational perfusion enhancement 5 yr patency 50%, secondary 75%
72
What are graft options for LE bypass?
SVG LSV superficial FV arm vein endarterectomized seg of SFA cryopreserved vein PTFE ePTFE contr vein
73
What % of contra vein is used for future surgery?
20-25%
74
What is the advantage of a vein cuff for LE bypass
may improve patency by 2-3 years with cuff and PTFE 2 yr patency 50% vs 30%
75
What is the difference between miller, taylor, st marys boot?
miller---rim of vein circum, then ptfe sewed to rim taylor patch--patch on toe of anastomosis (half artery, half ptfe) sta mary boot--rim of vei nthat folds around on itself vein then comes off the top
76
What are correction rates for intra-op imaging for LE bypass?
arteriography 27%--may not see incomplete valve lysis DUS 12% (psv \>250)
77
What are patency rates of dacron vs ptfe for AK bypass? HUV vs PTFE for AK? PTFE cuff vs no cuff? AK pop vein vs prothetic? BK pop vein vs prosthetic? infrapop vein vs prothetic?
1 yr 70% for both, 5 yr 50% 5 year 70 vs 40 (but some studies show not difference) AK no diff, 1 yr 80% BK 80 vs 65% 1 yr 60 vs 40% no signif 75 vs 55 70 vs 15%
78
What is the benefit of warfarin therapy for infr-inguinal bypass? insitu vs reversed?
warfarin benefited prothetic graft patency but at double bleeding complications no difference
79
what is a schedule for post-op graft surveillance? what is the benefit of graft surveillance
4week 3 month x 1 year 6month x 2 yr then yearly improves patency by 15%
80
what are duplex criteria for impending infrainguinal graft failure?
velocity \>300cm/s velocity ratio \>3.5-4 drop in ABI 0.15 prophylactic repair
81
what are causes of early graft failure?
early anastomotic, clamp defect, valve defect, poor quality conduit, inadequate outflow
82
What are techniques for treating stenosis or late occlusion?
patch, interposition, valve excision, plasty, anastomotic translocation thrombectomy, lysis, redo with vein or prosthetic
83
What are TASC A lesion for fempop?
single O \<5cm single s \<10
84
What are TASC B for fempop?
multiple stenosis or collusion each \<5cm SS/O SFA \<15 S/M lesions with no continuous runoff Heavily calcified occlusion \<5 single pop stenosis
85
What are TASC C lesions for fempop?
multiple stenosis or occlusions total \>15cm recurrent stenosis or occlusion after 2 endo attempts
86
what are Tasc D lesions for fem pop?
CTO of CFA/SFA CTO of pop and prox trifurcation
87
What are TASC A lesion for infrapop?
singel stenosis \<1cm in tibials
88
What are TASC B lesions for infrapop?
multiple stenosis of tibials each \<1cm at trifurcation short tibial stenosis with fempop PTA
89
What are TASC C lesions for infrapop?
stenosis 1-4cm occlusions 1.2 cm of tibials extensive stenosis of trifurcation
90
What are TASC D lesions for infrapop?
tibial occlusion \>2cm diffusely dz tibials
91
What are determinants of succes in endovascular?
improvement in at leas one rutherford and ABI increase \>0.15 absence of stenosis \<200
92
What are favorable characteristics for endovascular therapy?
proximal location stenosis short stenosis length focal stenosis single level dz normal runoff male low comorbidities IC primary attemot no residual stenosis or dissection robust hemodyn response
93
What is patency difference for lesion \> or \< then 2 cm? focal vs multifocal? good vs poor runoff?
5 yr 75% vs 50% 70% vs 20% 50 vs 30%
94
What are 1,2,3 year success rates for endo in LE for endo vs open?
40, 20, 10 endo 85, 70, 70 open
95
How successful is angioplasty for fempop dz? angio vs bypass? angio vs stenting? DES? DCB vs POBA?
3 yr PP for stenosis in IC 60% occlusion in IC 50% stenosis in CLI 45% occlusion in CLI 30% BASIL, if lives \>2 years open better lesion greater then 5cm benefit from primary stenting sirocco II failed to show improvement with DES for restenosis DCB better at 6 months
96
What is patency of angio for infrapop? difference in angio vs stenting?
1yr 75% 3yr 60% no difference
97
wha is patency for laser atherrectomy?
1 yr 75%
98
What is benefit of DES in infrapop endo?
3 yrs everolimus had higher PP then BMS 30 vs 20
99
What is plasty/stenting surveillance?
ABI, PVR, Duplex 1,3,6,9,12 months then yearly
100
what is patency of CFA steting?
3 yr patency 80%, surgery recommended
101
What is endo not indicated for PFA?
usually not suitable because of ostial, bifurcation and diffuse
102
What are cholesterol targets for PAD? BP? HbgA1C
sympto/asympto PAd LDL 100mg/dL PAD and vascular dz in other beds 70mg/dL \<7%
103
What medications should PAD patients be on, TASC?
ASA beta-blocker peri-op cilostazol first line for relief of claudication
104
What is an alternative way to test for IC if ABI unreliable?
treadmill test active pedal flexion inflate cuff for 3-5 minutes, this produces reactive hyperaemia, measure pressure 30sec after deflating cuff
105
What is critical TcPO2 level?
\<30mmhg
106
What are the principles of ulcer management?
restoration of perfusion local ulcer and pressure relief treatment of infection diabetic control
107
What are the treatment of choice for different TASC lesions for AI or fempop?
TASC A endo TASC D open TASC B endo preferred TASC C open preferred if good risk
108
What is 5 yr latency for ABF? is it better then endo?
70% in CLI 80% in IC better ing term latency but higher risk
109
What is the Crawford Classification?
Type I LSCA to diaphragm Type II LSCA to bifurcation Type III T6 to to bifurcation Type IV T6 to renals Type V T6 to above renals
110
Things to ask when imaging aorta?
Location of abnormal Max diameter If genetic syndrome, av sinus, STJ, asc aorta diam Filling defects Presence if IMH, PAU, calcification Extension into branches end organ injury Presence of rupture hematoma Previous imaging
111
What are the indications for surgical treatment for ascending aorta?
Class I Asympto aneurysm, asc, root, IMH, PAU, mycoric pseudo \>5.5 cm Asympto growth rate \>o.5 cm per year Asympto plus cv sx \>4.5 cm Sympto Modified David if possible for marfans LD, EHD
112
What is risk for asc/thoracic repair?
MI 1-5% Infection 1-5% Stroke. 1-2% Reop 1-6% Resp failure 5-15% Paralysis 2-4% increase in extent II
113
What are causes of TAAA?
Degenerative 82% Dissection 17% CTD
114
What are the Indications for desc aneurysm/TAAA?
Class I If chronic dissection \>5.5cm If defen/traumatic \>5.5cm or saccular or pseudo EVAR recommend If EVAR not commended and TAAA then 6.0 cm
115
What inflamm dz are associated with TAA and dissection?
Takayasau. T cell mediated para arteritis Giant cell arteritis- elastic vessel vasculitis Behcet Ank spon Infective
116
What bacteria are common in infected aorta?
S. Aureus, salmonella most common Pneumococcus and E. coli most common gram negative Treponema pallidum Candida/aspergillus
117
Before stenting defending what do you need to confirm before covering LSCA? What conditions increas risk of paraplegia when stenting?
Contra r subclavian and verts are patent Verts communicate via basilar artery Previous AAA 10% vs 2%
118
What is the endoderm classification?
Type I leak at attachment site Ia proximal, Ib distal, Ic iliac occluder Type II branch vessel, IIa single vessel, IIb 2 or more Type III defect in great IIIa junction of component, IIIb wint graft defect Type IV. Graft porosity Type V Continued expansion without demonstrating leak endotension
119
Which endoleak is most common? Which endoleak considered unresolved? What percentage are these? How to deal with type II? Does type IV require tx?
II 80% I 10% Can resolve spon or add occluder NO
120
What are indications for definitive management for acute aortic disease?
Asc urgent repair Desc Medical management unless complicated
121
What is medical management of acute aortic disease?
Class I IV BB HR 60 SBP\<120 If BB CI then CCB If SBP \>120 with adequate HR use second vasod or ACEi
122
In what condition should BB and AoD be administered cautiously?
AI with AoD Will block compensatory tachy
123
What is natural he of type A dissection? Surgical mortality? Survival?
50% die immediately then 1% per hour 10% 50-70% alive at 5years
124
What is natural history of type B? What is mortality of treated?
50% mort untreated 9% hospital mortality
125
What are indications for arch replacement?
Class IIa Entire arch if dissected or leaking Low operative risk and asympto \>5.5cm Growth rate \>0.5 cm per year
126
What is operative mortality for arch aneurysm? Stroke rate? Ten year survival?
Mort 9% Stroke 7% 60-70%
127
How do you treat arch/thoracic atheroma embolic dz? What is natural hx?
IIa Warfarin or anti PLT in stroke patients with atheroma \>4mm 1/3 progress 10% regress
128
What are bindi cations for BP management for thoracic aneurysmal dz? And cholesterol?
Class I BP \<140/90 or 130/80 if diabetic/CRD BB to all marfans IIa BB to decrease SBP as low as tolerated IIb LDL \<70 mg/dl for atherosclerosis dz, aneurysm CAD or high risk for CAD
129
What mutations are associated with Marfans Loeys dietz Ehlers danlos type IV Turners Familial thoracic aneurysm
FBN1. Fibrillin, increase penetrate with variable penetration TGBFR1, TGBFR2, autosomal dom COL3AI, type III collagen, autosomal dom 45X ACTS2 14%, TGBFR2 4%, MYH11 1%
130
What are surgical I medications for marfans, loeys dietz and ED for asc and root?
Marfans \>5.0 cm unless fam hx rupture \<5.0 cm, growth rate \>0.5cm year, signif AI LD \>\= 4.2cm by TEE internal, 4.4-4.6 by ct MRI external, ED UV not recommended for prophylaxis
131
What are main clinical findings in marfans?
Ocular skeletal cardiovascular
132
At what size can offer elective repair for root in marfans before conception? If becomes pregnant what to do ? When is guest risk?
4.5cm Abort Third trimester for dissection rupture
133
What is natural hx of TRA? How to tx? Mortality with tx?
20% MVA at autopsy 10-15% of them arrive to hospital alive 2% survive Stent 1.5% mortality
134
What are features of TRA on CXR?
Widened mediastinum 8-8.5cm Deviation of the esophagus Trachea \>1-2cm to the right of spinous process
135
When is thoracotomy indicate in penetrating mediastinal wound?
\>1500-2000ml blood loss within first four hours 200-300ml per hour for 4-5 hours Chest greater then half full despite chest tube Positive arteriography for vessel injury
136
What % of blunt trauma have pericardial tear? What are common injuries to heart with blunt trauma?
37% Tear RA at junction of IVC/SVC, VS, ASD (Rare), AI
137
What percent of trauma have myocardial contusion? What are the most frequent sites? Comps of contusion? TX of contusion?
90% Ant right ventricular wall then and intervention septum and LV apex Arrhytmia and myocardial contractility 10-20% EKG 12-24 hours, serial troponins, TTE, monitored bed
138
What is the Crawford Classification?
Type I LSCA to diaphragm Type II LSCA to bifurcation Type III T6 to to bifurcation Type IV T6 to renals Type V T6 to above renals
139
Things to ask when imaging aorta?
Location of abnormal Max diameter If genetic syndrome, av sinus, STJ, asc aorta diam Filling defects Presence if IMH, PAU, calcification Extension into branches end organ injury Presence of rupture hematoma Previous imaging
140
What are the indications for surgical treatment for ascending aorta?
Class I Asympto aneurysm, asc, root, IMH, PAU, mycoric pseudo \>5.5 cm Asympto growth rate \>o.5 cm per year Asympto plus cv sx \>4.5 cm Sympto Modified David if possible for marfans LD, EHD
141
What is risk for asc/thoracic repair?
MI 1-5% Infection 1-5% Stroke. 1-2% Reop 1-6% Resp failure 5-15% Paralysis 2-4% increase in extent II
142
What are causes of TAAA?
Degenerative 82% Dissection 17% CTD
143
What are the Indications for desc aneurysm/TAAA?
Class I If chronic dissection \>5.5cm If defen/traumatic \>5.5cm or saccular or pseudo EVAR recommend If EVAR not commended and TAAA then 6.0 cm
144
What inflamm dz are associated with TAA and dissection?
Takayasau. T cell mediated para arteritis Giant cell arteritis- elastic vessel vasculitis Behcet Ank spon Infective
145
What bacteria are common in infected aorta?
S. Aureus, salmonella most common Pneumococcus and E. coli most common gram negative Treponema pallidum Candida/aspergillus
146
Before stenting defending what do you need to confirm before covering LSCA? What conditions increas risk of paraplegia when stenting?
Contra r subclavian and verts are patent Verts communicate via basilar artery Previous AAA 10% vs 2%
147
What is the endoderm classification?
Type I leak at attachment site Ia proximal, Ib distal, Ic iliac occluder Type II branch vessel, IIa single vessel, IIb 2 or more Type III defect in great IIIa junction of component, IIIb wint graft defect Type IV. Graft porosity Type V Continued expansion without demonstrating leak endotension
148
Which endoleak is most common? Which endoleak considered unresolved? What percentage are these? How to deal with type II? Does type IV require tx?
II 80% I 10% Can resolve spon or add occluder NO
149
What are indications for definitive management for acute aortic disease?
Asc urgent repair Desc Medical management unless complicated
150
What is medical management of acute aortic disease?
Class I IV BB HR 60 SBP\<120 If BB CI then CCB If SBP \>120 with adequate HR use second vasod or ACEi
151
In what condition should BB and AoD be administered cautiously?
AI with AoD Will block compensatory tachy
152
What is natural he of type A dissection? Surgical mortality? Survival?
50% die immediately then 1% per hour 10% 50-70% alive at 5years
153
What is natural history of type B? What is mortality of treated?
50% mort untreated 9% hospital mortality
154
What are indications for arch replacement?
Class IIa Entire arch if dissected or leaking Low operative risk and asympto \>5.5cm Growth rate \>0.5 cm per year
155
What is operative mortality for arch aneurysm? Stroke rate? Ten year survival?
Mort 9% Stroke 7% 60-70%
156
How do you treat arch/thoracic atheroma embolic dz? What is natural hx?
IIa Warfarin or anti PLT in stroke patients with atheroma \>4mm 1/3 progress 10% regress
157
What are bindi cations for BP management for thoracic aneurysmal dz? And cholesterol?
Class I BP \<140/90 or 130/80 if diabetic/CRD BB to all marfans IIa BB to decrease SBP as low as tolerated IIb LDL \<70 mg/dl for atherosclerosis dz, aneurysm CAD or high risk for CAD
158
What mutations are associated with Marfans Loeys dietz Ehlers danlos type IV Turners Familial thoracic aneurysm
FBN1. Fibrillin, increase penetrate with variable penetration TGBFR1, TGBFR2, autosomal dom COL3AI, type III collagen, autosomal dom 45X ACTS2 14%, TGBFR2 4%, MYH11 1%
159
What are surgical I medications for marfans, loeys dietz and ED for asc and root?
Marfans \>5.0 cm unless fam hx rupture \<5.0 cm, growth rate \>0.5cm year, signif AI LD \>\= 4.2cm by TEE internal, 4.4-4.6 by ct MRI external, ED UV not recommended for prophylaxis
160
What are main clinical findings in marfans?
Ocular skeletal cardiovascular
161
At what size can offer elective repair for root in marfans before conception? If becomes pregnant what to do ? When is guest risk?
4.5cm Abort Third trimester for dissection rupture
162
What is natural hx of TRA? How to tx? Mortality with tx?
20% MVA at autopsy 10-15% of them arrive to hospital alive 2% survive Stent 1.5% mortality
163
What are features of TRA on CXR?
Widened mediastinum 8-8.5cm Deviation of the esophagus Trachea \>1-2cm to the right of spinous process
164
When is thoracotomy indicate in penetrating mediastinal wound?
\>1500-2000ml blood loss within first four hours 200-300ml per hour for 4-5 hours Chest greater then half full despite chest tube Positive arteriography for vessel injury
165
What % of blunt trauma have pericardial tear? What are common injuries to heart with blunt trauma?
37% Tear RA at junction of IVC/SVC, VS, ASD (Rare), AI
166
What percent of trauma have myocardial contusion? What are the most frequent sites? Comps of contusion? TX of contusion?
90% Ant right ventricular wall then and intervention septum and LV apex Arrhytmia and myocardial contractility 10-20% EKG 12-24 hours, serial troponins, TTE, monitored bed
167
How does the normal aortic doppler signal appear superior and inferior to the renal arteries?
monophasic/biphasic flow triphasic flow
168
What are normal size measurements of the visceral vessels?
aorta 2-2.5 celiac 0.7 SMA 0.6 IMA 0.3 Renal 0.4-0.5
169
What is normal length of the kidneys? what is the normal size of the parenchyma? which kidney is usually bigger?
\>9cm \>13 large \>1 cm L\>R
170
What are velocities for aorta and renals?
aorta 60-120cm/s renal artery 160-180
171
What criteria suggest stenosis in the renal artery?
RA/Aorta velocity (RAR)\> 3.5 suggest \>60% stenosis need to correct for angle
172
What doppler criteria suggest RAS?
Main renal artery: RAR \>3.5 dampening of doppler waveform in segmental arteries acceleration index 70m/s
173
What are the RAS criteria?
% stenosis RAR PSV PSturbu N 180 no \>60% \>3.5 \>180 yes occluded N/A N/A N/A
174
What indicates portal hypertension?
MPV \>13mm absent variation in portal/splenic vein deminished portal flow hepato-fugal flow varices ascites/splenomeg PVobstruction turbulent hepatic artery flow
175
How do you know if a TIPS is malfunctioning?
no flow shunt PSV 190 cm/s change in shunt PSV by decrease of \>40cm.s or increase in \>60cm/s MPV PSV \<30cm/s reversal of flow in hepatic veins hepatopedal intrahepatic portal venous flow
176
what is the resistive index? and waht is abnormal?
RI=PSV-EDV/PSV 0.6 (with 0.7 upper limit of normal)
177
what is abnormal MPV size?
\>13mm
178
what is abnormal spleen size?
\>15mm