Albuterol Sulfate

Question 1

Albuterol
Classification

Answer 1

Sympathomimetic
Sympathetic agonist (B2 selective)

Question 2

Albuterol
Mechanism of Action

Answer 2

B2 agonist: promotes sympathetic stimulation of bronchial smooth muscle cells, reducing interaction between actin and myosin causing smooth muscle relaxation-bronchodilation

Question 3

Albuterol
Onset of Action

Answer 3

5-15 min

Question 4

Albuterol
Peak Effect

Answer 4

1.0-1.5 hrs

Question 5

Albuterol
Duration of Effect

Answer 5

3-6 hrs

Question 6

Albuterol
Half-life

Answer 6

<3 hrs

Question 7

Albuterol
Indications/Field Use

Answer 7

*Reversible bronchospasms associated with COPD and asthma
*Wheezing associated with allergic reaction/anaphylaxis

Question 8

Albuterol
Contraindications

Answer 8

Symptomatic tachycardia
Hypersensitivity

Question 9

Albuterol
Side Effects/Adverse Reactions

Answer 9

Anxiety
HA
Palpitations
Sweating
Dizziness
Nervousness
Tremor
HTN
Dysrhythmias
CP
N/V

Question 10

Albuterol
Adult Dose

Answer 10

Nebulizer 2.5 mg in 2.5ml NS with O2 at 8LPM

Question 11

Albuterol
Pedi Dose

Answer 11

Nebulizer 2.5 mg in 2.5ml NS with O2 at 8LPM

Question 12

Albuterol
Precautions

Answer 12

May worsen cardiac asthma and precipitate dysrhythmias
Consider 12-lead in pts associated with CP

Question 13

Albuterol
Drug-drug Interactions

Answer 13

SE may increase with other sympathetic agonists
B blockers may blunt effects of this drug
MAOI and TCA may potentiate cardiovascular effects