Alcohol Flashcards

(69 cards)

1
Q

what is the dominant view of alcoholism?

A

it is a chronic disease -cant be cured unless pure abstinence is practiced

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

when was the concept of alcoholism as a disease first introduced?

A

1960, jellinek wrote a book about it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what greek letter did jellinek define a true alcoholic by?

A

gamma- the indv. with the disease alcoholism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what was the criteria to be a gamma drinker?

A

1) if someone with alcoholism doesnt stop drinking they will have severe mental and physical effects
2) drinker experiences ‘loss of control’ when drinking (cant control how many they have)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is the correct term? recovering or recovered alcoholic?

A

recovering- never can be fully recovered (like diabetic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is the only solution when looking at alcoholism as a disease?

A

total and complete abstinence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is alcoholics anonymous? (AA)

A

a self help group that focuses on complete abstinence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

how was AA founded?

A

in 1935, by 2 alcoholics, Dr. bob and bill

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how many steps are in the AA program?

A

twelve principles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is the alternative to abstinence as the only treatment to alcoholism?

A

reduced and controlled drinking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

why is reduced/controlled a better solution?

A

1) drinkers avoid treatment bc fear of abstinence
2) 80% of americans think not drinking is anti-social
3) becoming abstinent doesnt fix all your life problems
4) teaching the ‘one drink away from drunk’ philosophy might be a self fulfilling prophecy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what hypothesis is the treatment of reduced/controlled drinking based in?

A

drinking is a learned behaviour shaped by reinforcement, and can be controlled by changing the sources of reinforcement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

who did studies on alcoholism can be modified by reinforcement in the 60’s and 70s?

A

mello and mendelson pg 55

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

how did delay in reward affect abstinence?

A

most only sought immediate gratification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what happened if there were rewards given regardless f amount of alcohol consumed?

A

drinkers had no motive to control their drinking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what did the study regarding loss of control being due to expectancies of alcohol result in?

A

telling the ppl there was alcohol in beverage = ^ consumption, ^ intoxication, ^ in withdrawal symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

who did the groundbreaking research on controlled drinking?

A

mark and linda sobell, patton state hospital

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what did the controlled drinking study reveal about alcoholism?

A

that controlled drinking program was more effective in the long term

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what is harm reduction approach to drug use?

A

where you use strategies to reduce level of drinking, though abstinence is ideal its more realistic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what are knockout animals in science?

A

where specific genes can be turned on or off to determine genetic differences

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what three strains of mice were used to test genetic effect on alcoholism?

A

C57BL, DBA, BALB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

which mouse strain was more resistant to alcohol and could consume more?

A

C57BL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what is selective breeding?

A

breed high interest rats together, breed low interest rats together, until there becomes two extremes (avoid alcohol or prefer alcohol over water)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what are the two kinds of rats developed from selective breeding?

A

alcohol accepting- AA

alcohol non accepting- ANA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
what other kinds of selectively bred rats exist for the study of alcoholism?
SS- short sleep -not affected by alcohol LS- very affected by alcohol WSR- withdrawal seizure resistent- no withdrawal WSP -withdrawal seizure prone -bad withdrawal
26
what interesting attribute do alcohol preferring rats display?
they prefer saccharine solutions (ie. sweet tooth)
27
are alcohol preferring rats less or more sensitive to alcohol?
less sensitive, more tolerant
28
t/f: alcoholics display a sweet tooth phenomenon
true
29
what kind of knockout mice had reduced reinforcement from alcohol?
CB1 cannabinoid receptor knockouts
30
what kind of knockout mice drank less alcohol and were less effected?
lacked serotonin receptors
31
t/f: knockout mice missing mu opiate receptors showed more evidence of alcohol reinforcement
false; less reinforcement from alcohol
32
what 3 studies determine heritability of a characteristic?
family, twin, and adoption studies
33
t/f: one or both alcoholic parent will increase liklihood to be alcoholics
true
34
est. rate for alcoholic sons to develop vs daughters
50% vs 10%
35
what is concordance in twin studies?
the similarity of a characteristic between twins (identical will be more similar than fraternal)
36
what is the formula for calculating heritability?
heritability= 2 (r MZ - r DZ) MZ: monozygotic aka identical DZ: dizygotic aka fraternal
37
what is the concordance rate for identical twins?
60%
38
what is the concordance rate for fraternal twins?
25%
39
what is the total heritability estimate for alcoholism?
70%
40
there are 2 kinds of alcoholism, what are they?
1) type 1 -nonfamilial (environmental AND genetic), mental illness related, after age 25 2) type 2 - familial (inherited), mostly males, before age 25
41
which type of alcoholic is thought to be the 'gamma' alcoholic?
type 2 -familial
42
are adopted children away from alcoholic parents at any less risk for developing alcoholism?
nope
43
what are trait markers?
chars that determine if a person is at risk for developing alcoholism
44
what are the two options of trait markers?
positive family history (FH+) or negative family hisotry (FH-)
45
is there a difference between alcohol absorption in FH+ AND FH- people?
nope
46
which FH person has slower breakdown of acetyaldehyde?
FH+, have higher blood acetaldehyde levels
47
what contributes to FH+ having more 'flushing' reaction to alcohol?
slower breakdown of acetyaldehyde
48
why are certain ethnic groups protected from alcoholism?
the flushing effect
49
what is the p300?
a +ve voltage that happens 300 msec after seeing a stimulus
50
what is the p300 associated with?
the oddball effect
51
do FH+ or FH- have a faster recovery time for p300?
FH+
52
which family history is less affected by alcohol?
FH+ are less affected
53
what is the stress dampening effect?
a bodily reaction to a stimulus (ex. shock) is dampened by alcohol
54
which group shows greater stress dampening effect from alcohol?
FH+ (it dampens stress more than FH-)
55
what did william c sullivan find when studying babies of alcoholic and non alcoholic babies?
the infant death/stillbirth rate was 2 1/2 x higher for alcoholics
56
what does fetal alcohol syndrome FAS entail?
facial abnormalities, fetal growth deficiency, behaviour/development delays, mental retardation/CNS problems
57
what are facial abnormalities seen in FAS?
bulging forehead, narrow upper lip, unparallel ears, upturned nose, short eye slits
58
what trimester do facial abnormalities occur?
first trimester
59
what trimester affects fetal growth?
last trimester- affects birth weight and length
60
what behavioural attribute is common in FAS children?
hyperactivity
61
t/f: learning and memory are impaired by prenatal alcohol
true
62
what % of FAS children score 2 SD below mean IQ?
85%
63
what trimester affects IQ and brain development?
first trimester
64
what is the rate of FAS children in live births?
10 out of 1000 births
65
what is the # of daily drinks where risk for FAS increases?
6 standard drinks
66
what # of drinks has been assoc. with cognitive deficits?
2 drinks a day
67
why does binge drinking increase risk of FAS?
the increased BAC level
68
what is the % of pregnant women that drink any alcohol?
20%
69
what is the % of pregnant women who binge drink?
4%