alendronic acid Flashcards
1
Q
type of drug
A
bisphosphonate
2
Q
MOA of alendronic acid
A
absorbed into hydroxyapatite crystals in bone
slows their growth and dissolution
reduced rate of bone turnover
3
Q
indication of alendronic acid
A
Tx of OP after DEXA scan
prophylaxis (LT/repeated steroid use)
4
Q
interactions of alendronic acid
A
chelation with foods or other drugs
5
Q
What should be taken with alendronic acid?
A
calcium
Vitamin D
6
Q
major s/e with alendronic acid
A
ONJ - rare, tell dentist
oesophageal rxns - oesophagitis, ulcers, take sitting up for 30mins
