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PCOG LEC > Alkaloids 2 - Part 1 > Flashcards

Alkaloids 2 - Part 1 Flashcards

1
Q

Sources of Strychnine and Brucine

A

Nux vonica

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2
Q

Scientific name for Nux Vonica

A

Strychnos nux vonica

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3
Q

Nux vonica is closely related to?

A

Strychnos ignatii

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4
Q

Strychnos ignatii is the commercial source of? (2)

A

Strychnine
Brucine

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5
Q

Strychnine is commonly marketed as? (2)

A

Strychnine sulfate
Strychnine Phosphate

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6
Q

Brucine is less toxic than _________ and is used commercially as __________

A

Strychnine
Alcohol Denaturant

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7
Q

Brucine is extremely _________

A

Bitter

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8
Q

Strychnine is extremely _________ and is used as an ________

A

Toxic
Central Stimulant

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9
Q

Strychnine fatal dose is _______ and can be used as a __________

A

60-90 mg
Vermin Killer

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10
Q

Alkaloid that results in tonic convulsions

A

Strychnine

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11
Q

What are the other names of Physostigma Bean?

A

Calabar Bean
Ordeal Bean

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12
Q

Physostigma bean is from the dried seeds of

A

Physostigma venenosum

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13
Q

% yield of Physostigma Alkaloid

A

not less than 0.15%

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14
Q

in 1846 __________ described the uses of seeds known as _______ by the natives of old Calabar

A

Darniell
Esere

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15
Q

Alkaloids found inCalabar (Physostigma) bean (4)

A

Physostigmine (Eserine)
Eseramine
Geneserine
Physovenine

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16
Q

Where is Physostigmine (Eserine) obtained?

A

Dried ripe seeds of Physostigma venenosum

17
Q

Use of Physostigmine (Eserine)

A

Reversable inhibitor for cholinesterases
Treatment for Glaucoma

18
Q

Indole Alkaloid in topical 0.25% form that is used to treat conjunctiva

A

Physostigmine sulfate
Eserine sulfate

19
Q

Other names for Ergot

A

Rye Ergot
Secale Cornutum

20
Q

Former term for ergot

A

Dried sclerotium

21
Q

Required % yield for ergot

A

0.15%

22
Q

Common name for ergot

A

Spurred rye

23
Q

It has been grown saprophytically in submerged culture

A

Claviceps paspali

24
Q

Accepted chemical name of isolysergic acid isomer of ergonovine

A

ergometrinine

25
Q

Ergonovine maleate has a _________________ effect that is noted 5 mins

A

oxytonic effect

PCOG LEC (21 decks)

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