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1
Q

Natural PCNs

A

V, G

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2
Q

Anti-Staph PCNs

A

Nafcillin
Oxacillin
Dicloxacillin

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3
Q

AminoPCNs

A

Ampicillin

Amoxicillin

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4
Q

Anti-PseudomonalPCNs

A

Ticarcillin

Piperacillin

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5
Q

1st gen cephalosporins

A

Cefazolin

cephalexin

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6
Q

2nd gen cephalosporins

A

cefoxitin

cefuroxime

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7
Q

3rd gen cephalosporins

A

ceftriaxone

ceftazidime

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8
Q

4th gen cephalosporins

A

cefepime

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9
Q

Carbapenems

A

imipenem/cilastatin
meropenem
ertapenem

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10
Q

B-lactamase inhibitors

A

ampicillin-sulbactam
amoxicillin-clavulonic acid
piperacillin-tazobactam

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11
Q

glycopeptides

A

vancomycin

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12
Q

fluoroquinolones

A

ciprofloxacin
levofloxacin
moxifloxacin

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13
Q

aminoglycosides

A

amikacin
tobramycin
gentamycin

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14
Q

Tetracyclines/glycyclines

A

minocycline
doxycycline
tigecycline

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15
Q

macrolides/ketolides

A

clarithromycin
azithromycin
telithromycin

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16
Q

lincosamides

A

clindamycin

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17
Q

oxazolidinones

A

linezolid

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18
Q

CURB-65

A

confusion
Uremia (BUN>19)
Resps (>30)
BP (4000, plt > 100000, temp> 36

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19
Q

Cell Wall inhibitors

A 
Cephalosporins
Carbapenems
Glycopeptides
Monobactams
PCNs
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20
Q

Monobactam

A

Aztreonam

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21
Q

DNA replication inhibitors

A

Flouroquinolones

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22
Q

Protein Synth Inhibitors 30S

A

Aminoglycosides

tetracyclines

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23
Q

Protein synth inhibitors 50S

A

clindamycin
linezolid
macrolides
streptogramins

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24
Q

Natural PCNs admin

A

G-IV, IM

V-PO

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25
Anti-staph PCN admin
nafcillin-IV, IM Oxacillin-IV, IM dicloxacillin-PO
26
AminoPCN admin
Ampicillin-PO, IV, IM | Amoxicillin-PO
27
Anti-pseudomonalPCN admin
IV
28
Cephalosporin 1st gen admin
cefazolin-IV, IM | Cephalexin-PO
29
Cephalo 2nd gen admin
cefoxtin-IV | Cefuroxime-PO, IV, IM
30
cephalo 3rd gen admin
ceftriaxone-IV, IM | Ceftazidime-IV, IM
31
cephalo 4th gen admin
cefepime-IV, IM
32
Carbapenems admin
imipenem/cilastatin-IV meropenem-IV ertapenem-IV, IM
33
Monobactam admin
aztreonam-IV, IM, INH
34
B Lactamase inhib admin
ampicillin/sulbactam-IV amoxicillin-clavulanic acid-PO Piperacillin/tazobactam-IV
35
glycopeptide admin
vancomycin-PO, IV
36
FQ admin
PO, IV, Topical
37
Aminoglycosides admin
amikacn-IV, IM Tobramycin-Iv, IM, IN, Topical gentamycin-IV, IM, Topical
38
Tetracyclines admin
minocycline-PO, IV doxycycline-PO, IV tigecyclin-IV
39
Macrolides admin
larithromycin-PO azithromycin-PO, IV, Topical telithromycin-PO
40
LIncosamides admin
clindamycin-PO, IV, IM, opical
41
Oxazolidinones admin
linezolid-PO, IV
42
No renal dose adjustgin
ceftriaxone | moxifloxacin
43
PCN MOA/R
inhibits cell wall synth | R: b lactamases, changes in PBPs
44
PCN SE
allergic rxns, GI, pseudomemb colitis, nephritis
45
cephalosporins MOA/R
cell wall synth | R: b lactamases, changes in PBPs
46
Cephalosporin Se
diarrhea, iintolerance to alcohol, cross reactivity to PCNs
47
Carbapenems MOA/R
cell wall synth | R" KPC carbapenemase
48
Carbapenems SE
N/V seizures hypersensitivity
49
Monobactam MOA/R
cell wall synth | R: b lactamases, changes in PBPs
50
Monombactam use
allergy to PCN, cephalosporings
51
Glycopeptides MOA/R
cell wall synth
52
Glycopeptides SE
rash, red man syndrome, ototox, nephrotox
53
FQ MOA/R
DNA gyrase R: no FQ modifying/inactivating entities mutation in DNA gyrase/topoisomerase
54
FQ SE
NVD CNS Rash, photosensitivity Achilles tendon rupture kids
55
Don't give to kids
FQ, tetracyclines
56
aminoglycosides MOA/R
30s, conc dependent | R; AG metabolizing enzymes, impaired trx of drug into cell, altered ribosome
57
aminoglycosides SE
ototox, nephrotox, neuromuscular block, apnea
58
Tetracyclines MOA/R
30s | R: dec influx, acquisition energy dep efflux, ribosomal protection proteins, enzymatic inactivation
59
Tetracyclines SE
GI, c diff superinfx, photosens, teeth discoloration, thrombophlebitis
60
Macrolides MOA/R
50s | R: drug efflux, ribosomal protection proteins, hydrolysis, ribosomal mutations
61
macrolides Se
Gi, hepatotox, arryhtmia, QT prolong
62
Lincosamides MOA/R
50s | R: ribosomal methylation
63
Licosamides Se
GI diarrhea, pseudomemb colitis (c dif), rash, inc ALTs, potentiate neuromusc block
64
Oxazolidinones MOA/R
50s | R: ribosomal mutation
65
Oxazolidinones Se
myelosuppression, GI, HA rash
66
Oxazolidinones drug intrx
SSRI

Antibiotx (3 decks)

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