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Pharmacology I > All Drugs - Class & Indication ONLY > Flashcards

All Drugs - Class & Indication ONLY Flashcards

(61 cards)

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0
Q

Propranolol (Inderal)

A

Non-specific (1&2) Beta adrenorecceptor blocker.

Use for anti-HTN, antiarrhythmic, primary and secondary MI prevention, anti-angina

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1
Q

Varenicline

A

Partial Nicotinic a2-a4 receptor agonist

Use for smoking cessation

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2
Q

Dopamine

A

Adrenergic and Dopaminergic agonist (inotrope)
Use for shock and CHF, will preserve kidney perfusion.
Stimulates DA receptors to INCREASE RENAL BLOOD FLOW

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3
Q

Epiephrine

A

Alpha 1 &2 and Beta 1 &2 adrenergic agonist

Use for Shock, anaphylaxis, or local anesthesia

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4
Q

Acetylcholine

A

Cholinergic agonist

Use for Glaucoma

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5
Q

Clonidine

A

Selective alpha adrenergic 2 agonist
ACTS CENTRALLY on a2 receptors to downregulate sympathetic tone.
Use to treat HTN or prevent migraine

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6
Q

Isoprotenerol

A

Beta 1+2 agonist

Use for bradycardia

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7
Q

Phenylephrine

A

Alpha 1 adrenergic agonist

Use to vaso/veno constrict for nasal decongestion, mydraisis, or to increase BP in dilated state.

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8
Q

Ephedrine

A

Indirect adrenergic, stimulates NE release

Use for mild hypotension during surgery or nasal congestion

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9
Q

Dobutamine

A

B1 agonist

Use to increase contractility MORE THAN HR in CHF where you don’t want tachycardia

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10
Q

Albuterol

A

B2 agonist

Use to bronchodilate for asthma or COPD

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11
Q

Phentolamine

A 
non selective (1 +2) alpha adrenergic BLOCKER
Use to decrease preload and afterload in HTN crisis
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12
Q

Pseudophedrine

A

Indirect adrenergic, causes release of NE and has some a and B agonism.
Use for nasal/sinus decongestant

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13
Q

Amphetamine

A

Inndirect adrenergic, stimulates NE, dopamine, and serotonin release.
Use in ADHD

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14
Q

Tyramine

A

Indirect adrenergic; releases NE and dopamine
Present in packaged foods -> Metabolized by MAO
Know that it can cause a hypertensive crisis in pateints on MAO inhibitors (an antidepressant)

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15
Q

Cocaine

A

Indirect adrenergic, BLOCKS REUPTAKE OF NE, Epi, DA

Use for anesthesia w local vasoconstriction: nose bleed or corneal surgery

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16
Q

Tamsulosin

A

Selecetive alpha 1 blocker
Preferentially blocks in prostate.
Use to relax bladder, prostate, ureter to improve urine flow (BPH)..

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17
Q

Phenoxybenzamine

A

Irreversible alpha blocker

Use for to reduce peripheral vasospasm

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18
Q

Prazosin (Minipress)

A

Selective alpha 1 adrenoreceptor blocker

Use to black vaso/venoconstriction for anti-HTN and Benign Prostate Hypoplasia

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19
Q

Norepinephrine

A

Alpha1&2, and weak Beta1 agonist

Use for SHOCK

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20
Q

Atenolol (Tenormin, Metoprolol)

A

Specific Beta 1 blocker.
Use to lower BP by reducing CO and less RAA activation.
LESS EFFECTIVE FOR STROKE PREVENTION

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20
Q

Carvedilol (Coreg)

A

Mixed alpha beta BLOCKER, (Like labetalol)

USE more for CHF

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22
Q

Labetalol (Trandate)

A

Mixed alpha beta blocker

Use for treating HTN and CHF. May also be appropriate with pheochromocytoma.

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22
Q

Bethanachol

A

Muscurinic Agonist

Use for neurogenic Ileus, urine retention (MAKES YOU SHIT AND PISS)

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23
Pilocarpine
Muscarinic agonist | Use for Open/Closed angle glaucomas. Causes sweat tears saliva.
25
Carbachol
Cholinergic agonist | Use as topical Glaucoma tx. Will constrict pupil (Sphincter muscle activation - MIOSIS)
26
Methacholine
Muscurinic agonist Stimulates M receptors in airway, causes bronchoconstriciton. Use to for asthma dx challenge.
27
Edrophonium
Short acting AChE INHIBITOR: an indirect cholinergic agonist | Use to Dx Myasthenia Gravis. (pts get stronger after dose)
28
Neostigmine
Intermediate acting AChE inhibitor; an indirect cholinergic agonist Use for myasthenia gravis tx, to treat post-op/neurogenic ileus, Reversing NMJ blockade. NEO CNS = NO CNS Penetration
29
Physostigmine
Intermediate AChE Inhibitor -> increase endogenous ACh Use for anticholinergic CNS TOXICITY (crosses BBB) Physostigmine PHYxes atropine overdose.
30
Organophosphates
Long acting AChE inhibitors, permanently inhibit AChE. Causes DUMBELLS Treat with atropine (Competative inhibitor - a M antagonist) and parlidoxime (regenerates AChE)
31
Pralidoxime
Regenerates AChE; use for organophosphate poisoning.
32
Metoclopramide
indirect cholinergic, stimulates ACh release | Use for neurogenic Ileus and nausea.
33
Atropine
Muscurinic BLOCKER | Use to treat bradycardia, organophosphate poisoning, and cardiac resuscitation
34
Scopolamine
Muscurinic BLOCKER Use for motion sickness SCale the POL on a pirate ship
35
Dicylclomine
Muscurinic blocker Use for irritable bowel syndrome (If there are DI-Cyclones coming at you, you might shit yourself, so take Dicyclomine)
36
Methscopolamine, Pirenzipine, Propantheline
Muscurinic Blockers, | Use for PEPTIC ULCER Rx
37
Oxybutynin
Muscurinic blocker | Use for bladder urgency in cystitis and spasms
38
Glycopyrrolate
Muscurinic blocker Use pre op to reduce airway secretions Can tx peptic ulcer
39
Tropicamide | Homatropine
Muscurinic Blockers, like atropine. | Use for mydriasis (Pupil dilation) and cycloplegia (paralyze ciliary muscle)
40
Benztropine
Muscurinic Blocker Acts in CNS -> use to treat parkinsons PARK the BENZtropine
41
Ipratropium
``` Short acting muscurinic blocker Aerosol delivered (sometimes w/ albuterol) to inhibit bronchoconstriction. Use for Asthma and COPD ```
42
Tiotropium
longer acting muscurinic blocker, | Like ipratropium, use for asthma or COPD. Longer actions.
43
Succinylcholine
Depolarizing Nicotinic Blocker Causes depolarization-desensitization blockade due to prolonged receptor occupancy @ NMJ. USE FOR SHORT SURGERY AND INTUBATIONS -rapidly cleared by plasma AChEs
44
Tubocurarine
non depolarizing nicotinic blocker | Causes surgical paralysis
45
Pancuronium
Non depolarizing nicotinic blocker | use for surgical paralysis
46
Rocuronium, Cisatracurium
Non depolarizing nicotinic blocker | use for surgical paralysis
47
Trimethaphan
Nn ganglionic blocker Blocks all ganglia, used for effects at sympathetic ganglia. Use to reduce BP in surgery (IV)
48
Botulinum
Indirect anticholinergic Cleaves SNARES to prevent ACh release -> causes flaccid paralysis. Used for wrinkle treatment.
49
HCTZ
Blocks reuptake of Cl and Na | Use for HTN
50
Clorthalidone
Thiazide diuretic | Use for HTN, slightly bettter duration and efficaccy than HCTZ
51
Lisinopril (Prinvil)
ACE i | Use to treat HTN or CHF while PRESERVING KIDNEY function and LV function after MI
52
Losartan
Angiotensin 1 Receptor blocker (blocks binding of Angiotensin II!) reduces vasoconstriction and aldosterone release Use for HTN or CHF and will preserve renal function
53
Nitroprusside (Nipride)
Venous and Arterial dilator; acts directly on vascular SM to produce CNN- and NO Use under close monitoring (ICU) for HTN crisis, or severe CHF, or controlled Hypotension during surgery
54
Hydralazine (apresoline)
Direct vasodilator; induced NO production in endothelium. | Use for HTN or CHF, but never as chronic monotherapy or edema/tachycardia will result
55
Verapamil
Calcium channel blocker | Use as anti-HTN, anti-angina, or antiarrhythmia. Inhibits coronary vasospasm
56
Nifedipine
Ca Channel Blocker | Use for HTN angina and arrhythmia
57
Amlodipine
Calcium channel blocker | Use for HTN, angina, and arrhythmia
58
Diltiazem
Ca Channel blocker | use for anti HTN anti angina anti arrhythma
59
Methyldopa
Alpha 2 agonist, central acting, | Use for HTN
60
Reserpine
Blocks NE uptake, depleting NE | Used for HTN, may cause depression

Pharmacology I (2 decks)

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