all google forms quizzes Flashcards

1
Q

What are cell junctions?

A

intercellular bridges made up of structural proteins that allow cells to communicate

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2
Q

Gap junctions are gated channels which can change in permeability, TRUE OR FALSE

A

TRUE

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3
Q

Which of these are mainly found in tight junctions?
1- CONNEXONS
2- CLAUDINS AND OCCLUDINS
3- CADHERINS
4- ACTIN

A

claudins and occludins

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4
Q

Which of these are mainly found in gap junctions?
1- CONNEXONS
2- CLAUDINS AND OCCLUDINS
3- CADHERINS
4- ACTIN

A

connexons

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5
Q

which of these are mainly found in desmosomes?
1- CONNEXONS
2- CLAUDINS AND OCCLUDINS
3- CADHERINS
4- ACTIN

A

cadherens

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6
Q

plasmodesmata are found in all animal cells? TRUE OR FALSE

A

FALSE

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7
Q

what does the extra cellular matrix of an animal include?

A

collagen and fibronectin

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8
Q

which IS NOT a function of the extra cellular matrix?
1 - Space filler
2 - Prevent homeostasis
3 - Influence tissue development
4 - Regulate molecular movement

A

prevent homeostasis

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9
Q

X-linked Charcot-Marie-Tooth disease is linked to what type of junction?

A

gap junctions

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10
Q

Hyperkeratosis and onychodystrophy are linked to what type of junction?

A

desmosomes

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11
Q

Low magnesium and high calcium in the blood is linked to what type of junction?

A

tight junctions

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12
Q

If the immune system is triggered without ever reacting to an antigen, is it ACTIVE OR PASSIVE IMMUNITY

A

passive immunity

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13
Q

Does active or passive immunity work in an immunodeficient host

A

passive

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14
Q

is adoptive transfer active or passive immunity

A

passive immunity, as they’re being injected with another persons antibodies

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15
Q

what type of immunisation is mother to infant immunoglobulin transfer an example of

A

natural passive immunity

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16
Q

which immunoglobulin protects the foetus during development

A

IgG

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17
Q

do T cells increase or decrease in pregnancy

A

decreases

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18
Q

does the Th2 response increase or decrease in pregnancy

A

increases

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19
Q

what vaccination type(s) contain dead or inactive component of a pathogen

A

TIIV

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20
Q

In escape mechanisms, which of the below mutations leads to a different presentation at one specific site?
1 - Antigenic drift
2 - Antigenic shift
3 - Antigenic lift

A

antigenic drift

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21
Q

In escape mechanisms, which of the below mutations leads to a different presentation at multiple different sites?
1 - Antigenic drift
2 - Antigenic shift
3 - Antigenic lift

A

antigenic shift

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22
Q

Which of the below is an example of a toxoid vaccination
1 - Hepatitis A
2 - Tetanus
3 - Thyphoid
4 - Sars-COV-2

A

tetanus

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23
Q

what does LAIV stand for

A

live attenuated influenza virus

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24
Q

what does ADCC stand for in monoclonal antibody therapy

A

Antibody dependant cellular cytotoxicity

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25
what monoclonal antibody mechanism results in phagocytosis
CDCP
26
what is a eukaryote
a cell or organism with a clearly defined membrane bound nucleus
27
what is a prokaryote
a cell or an organism without a clearly defined membrane bound nucleus
28
define species
a group of similar organisms that can interbreed to produce fertile offspring
29
Microbes which live and thrive on the human body could be an example of what?
mesophiles
30
a mid halophile is an example of a microbe which prefers what type of condition
salt
31
what is a microbiome
The genetic material of all of the microorganisims in one specific environment or location at one time
32
Which of the below is NOT a function of commensal bacteria in the lungs? 1 - Trigger the immune response 2 - Recognise external invaders 3 - Allow colonisation of pathogenic bacteria 4 - Produce antimicrobial products and signals
allow colonisation of pathogenic bacteria
33
How are spermatozoa adapted to carry out its function?
They have enzymes to break down external layers of the ovum
34
How are the ovum adapted to carry out their functions?
they have protective external layers for species specific recognition
35
Which of the below is a strength of cell culture? 1 - Have a limited lifeline 2 - Have reduced hetrogeneity 3 - Continual maintenance required 4 - Can control the micro-environment
can control the micro environment
36
Which of the below is a limitation of cell culture? 1 - Have a limited lifeline 2 - Have been used to reduce animal testing 3 - Can be stored long term 4 - Can control the micro-environment
they have a limited lifeline
37
What is primary endosymbiosis?
where a eukaryotic cell engulfs a prokaryotic cell
38
what is secondary endosymbiosis
Where a eukaryotic cell engulfs a eukaryotic cell
39
what is the main organelle discussed in relation to serial endosymbiosis
mitochondria
40
what is bacterial redundancy
When multiple bacteria fill the same role
41
what is dysbiosis
a change in microbiome from healthy to diseased
42
what does CD in cell mediated immunity stand for
cluster of differentiation
43
Major Histocompatibility Complexes are a large group of genes which code for proteins that play an essential role in which of the below? 1 - Phagocytosis in macrophages 2 - Phagocytosis in neutrophils 3 - Antigen presentation in T lymphocytes 4 - Antigen presentation in B lymphocytes
antigen presentation in b lymphocytes
44
Allergies and tumour progression are liked to which type of Th cytokine?
Th2
45
Which enzyme is involved in caspase activation to cause apoptosis
granzyme B
46
Organ specific autoimmune disorders can be linked to which Th cytokine?
Th1
47
Which type of T cell mainly expresses CD16?
natural killer cell
47
Which type of T cell ensures self tolerance by CD25+ activation
regulatory T cell
48
Which CD combinations are found on early T cells?
CD4-CD8-
49
What does the 'H' in MHC stand for?
histocompatability
50
What does the 'A' in HLA stand for?
antigen
51
If T cells interactive with MCH class II, which types are they?
helper T cells
52
Which T cell is found in the highest percentage in the blood, lymph nodes and spleen?
helper T cell
53
Which type of antigen is presented as a class I MHC?
endogenous antigen
54
Exogenous antigens such as bacterium are presented as
MC class II
55
What is the name of molecules found on APCs which function with antigens to activate T cells
costimulators
56
If T cells interactive with MCH class I, which type are they?
cytotoxic T cells
57
which is the shortest phase of the cell cycle
M
58
cyclins are only active when they are bound to cyclin dependant kinases. TRUE OR FALSE
TRUE
59
is retinoblastoma a tumour suppressor
true
60
do protein kinases phosphorylate or dephosphorylate proteins
phosphorylate them - which leads to their activation
61
what is a key feature of cyclins
they're cyclical
62
what is the role of p35
to stop the cell at G1S and G2M phases for spindle repair to take place
63
what molecule does retinoblastoma release that allows cells to transition into G1/S
E2F
64
What is p35 known as
the guardian of the genome
65
which cyclin allows the cell to enter mitosis when activated
cyclin B
66
what is CREB activated by
phosphorylation by protein kinase A in the cytoplasm
67
what molecule is activated in G-protein receptor signalling
adenylyl cyclase
68
what is protein kinase A activated by
binding of cAMP to its regulatory subunits
69
Which of the following are examples of second messengers? 1 - cAMP 2 - cGMP 3 - Ca2+ 4 - Phospholipids 5 - all of the above
all of the above
70
what are G proteins
molecular switches that use GDP to control their signalling cycle
71
what is paracrine signalling
signal is sent from a nearby cell to induce a change
72
The GTP on the G protein that is linked to adenylyl cyclase is split to GDP and Pi.... 1 - in the inactive state 2 - in the process of subunit separation 3 - upon activation by the receptor 4 - by the active alpha subunit
by the active alpha sub unit
73
what is the effect of acetylcholine on heart muscles
decreases the rate of beating
74
during the phagocyte practical what was carmine red used for
to dye the sample to view the change in
75
during the phagocyte practical what was glutaraldehyde used for
to fix the sample
76
during the phagocyte practical what was ethanol used for
as a negative control
77
during the phagocyte practical what did the change in red vesical number show us
the measurement of phagocytosis occurring
78
during the phagocyte practical what was the change in black vesical a measurement of
egestion
79
In the Tetrahymena lab, which cellular structure does Colchicine inhibit the formation of?
microtubules
80
which type of cell junction is involved in neurulation
adherens
81
Which stage in serial endosymbiosis involves a prokaryotic cell being engulfed by a eukaryote?
primary endosymbiosis
82
If T cells interactive with MCH class I, which of the below cell types are they?
cytotoxic T cells
83
which organelle is affected by Parkinson's disease
mitochondria
84
what is the normal role of an organelle which if defective may cause EBS
structural support
85
is an inverted microscope used o view cell cultures
YES
86
what is pRB and what's its role
its a tumour suppressor and it inhibits the growth of tumours by inhibiting cell division
87
which organelle packages proteins
golgi
88
Which of the below monoclonal antibody mechanisms result in phagocytosis ?
ADCP
89
What is the name of molecules found on APCs which function with antigens to activate T cells
co-stimulators
90
Are Lipid bilayers are typically asymmetrical
no
91
Which phase of the cell cycle is the most metabolically active?
G1
92
Which statement is NOT true about microtubules 1 - They help organise cells during division 2 - They are important for cilia 3 - They polymerise and depolymerise constantly 4 - They strengthen cell junctions
they don't strengthen cell junctions
93
In G-protein coupled receptor signalling, what are RGS?
regulators
94
what is the role of acetylcholine in the heart
decreases the rate of beating
95
what is p53
the guardian of the genome
96