Allergy and Immunology Flashcards Preview

USMLE Step 3 > Allergy and Immunology > Flashcards

Flashcards in Allergy and Immunology Deck (21):
1

- hemodynamic instability (hypOtension/tachycardia)
- difficulty breathing
- d/t foods, insect stings/bites, medications

anaphylaxis

2

anaphylaxis treatment

1. epinephrine 1:1,000 INTRAMUSCULAR
2. corticosteroids
3. diphenhydramine or hydroxyzine

3

- sudden swelling of face, palate, tongue, and airway
- minor trauma to face and hands, or ingestion of ACE inhibitor
- C1 esterase inhibitor DEFICIENCY

angioedema

4

diagnosis of angioedema

low levels of C2 and C4 in complement pathway

5

treatment for angioedema: ACUTE episode

FRESH FROZEN PLASMA

6

treatment for angioedema: CHRONIC episodes

- ecallantide, or icatibant = DOC
- danazol, or stanozolol (androgens)

7

- nasal itching
- stuffiness
- rhinorrhea
- paroxysms of sneezing

allergic rhinitis

8

mainstay treatment for allergic rhinitis

avoidance of allergen

9

single most effective treatment for allergic rhinitis

intranasal corticosteroids

10

cromolyn MOA

stabilize mast cells preventing degranulation of histamine and leukotrienes

11

what MUST be stopped before DESENSITIZATION therapy

beta blockers

12

- may only present as an ADULT
- recurrent sinopulmonary infections
- sprue-like abdominal disorder

common variable immunodeficiency (CVID)

13

test for common variable immunodeficiency (CVID)

total IgG level

(will be LOW)

14

treatment for common variable immunodeficiency (CVID)

IVIG

15

- male CHILDREN
- recurrent sinopulmonary infections

X-linked Agammaglobulinemia (Bruton's)

16

diagnostic testing for X-linked Agammaglobulinemia (Bruton's)

1. LN's, adenoids, and spleen are diminished
2. no B cells = no immunoglobulins

17

treatment for X-linked Agammaglobulinemia (Bruton's)

IVIG

18

- most common primary immunodeficiency
- recurrent sinopulmonary infections
- sprue-like malabsorption syndrome
- atopy
- ANAPHYLAXIS WITH BLOOD TRANSFUSIONS

IgA deficiency

19

treatment for IgA deficiency

treat infections

20

recurrent Staphylococcus skin infections

hyper IgE syndrome

21

treatment for IgE syndrome

treat infections