Allergy/Immuno

Question 1

triggers for vasomotor rhinitis

Answer 1

cold air, tearing, pollution and emotion

Question 2

gold standard of dx food allergy is

Answer 2

oral food test in front of cliniciNS

Question 3

what kind of allergy testing isnt affected by recent antihistamine use

Answer 3

RAST since is a blood test measuring for IgE

Question 4

C1 esterase deficiency causes whst

Answer 4

hereditary angioedema

Question 5

what medicine blunts the effects of epinephrine and should be reversed if the patient is having anaphyaxis and needs epi

Answer 5

beta blocker, give glucagon to reverse

Question 6

what formula should you use for milk protein allergy

Answer 6

hydrolyzed not SOY

Question 7

is FPIES IgE mediated

Answer 7

no

Question 8

when does FPIES get better

Answer 8

as the GI tract matures

Question 9

Bloody diarrhea or reg diarrhea and emesis in a patient drinking cows formula but not when on clears and eating foods with none whole protein contents , dx?

Answer 9

FPIES

Question 10

what is food protein induced enterocolitis syndrome

Answer 10

a severe reaction to an allergen about 1-3 hours after ingestion, severe vomiting and diarrhea (cows milk and soy are culprits)

Question 11

hydrogen breath test tests for what

Answer 11

lactase deficiency

Question 12

type 3 HS reaction is?

Answer 12

immune complex

Question 13

ype 4 HS reaction is

Answer 13

cell mediated ( t cell) “poison ivy”

Question 14

type 2 HS reaction is

Answer 14

antibody mediated “ b cell”

Question 15

type 1 HS reaxtion is

Answer 15

IGE mediated anaphylaxis

Question 16

what medication blunts the response to epi? what should you give

Answer 16

beta blokers, give glucagon to reverse the effects

Question 17

anaphylactoid reactions happen in reponse to whatr

Answer 17

contrast, PCN, vanc, NSAID and opitates

Question 18

what should be given to prevent an anaphyactoid reaction

Answer 18

diphenhydramine and steroids

Question 19

nephritis, arthralgias, arthritis and or rash after exposure to medication 1-2 weeks prior is known as

Answer 19

serum sickness

Question 20

bee sting reactions are due to what

Answer 20

IgE mediated (type 2 HS rxn)

Question 21

bee sting reactions are due to what

Answer 21

IgE mediated (type 2 HS helper t cells rxn)

Question 22

bee sting reactions are due to what

Answer 22

IgE mediated (type 2 HS rxn)

Question 23

helper t cells

Answer 23

CD4

Question 24

Cytotoxic t cells

Answer 24

CD8

Question 25

PJP is found in SCID and HyperIgM but not in

Answer 25

Bruton Agammaglobulinemia

Question 26

chronic or recurrent fungal infections is seen in what kind of condition

Answer 26

t cell/ combined t cell deficiencies

Question 27

skin testing like ppd check for what kind of HS rexn

Answer 27

Type 4

Question 28

SCID is what kind of cell deficiency

Answer 28

t AND b cells " thats why it is called combined"

Question 29

first 3–6 months with otitis media (OM), thrush, diarrhea, and dermatitis.

Answer 29

SCID

Question 30

what is the cure for SCID

Answer 30

BMT

Question 31

what should SCID patient's not receive

Answer 31

live vaccines

Question 32

what are two common combined t and b cell deficiences

Answer 32

wiskott aldrich and SCID

Question 33

lymphopenia is usually in relaiton to what cell line being low

Answer 33

t cells

Question 34

what imunoglobulin is increased in WIA

Answer 34

IgA, IgM is dereased

Question 35

what test is used to dx digeorge

Answer 35

FISH

Question 36

what is an AR condition that involves the ineffective repaire of damaged DNA

Answer 36

ataxia telengeictasia

Question 37

1st sig of ataxia telengiectasia

Answer 37

cerebellar ataxia around age 1

Question 38

ataxia telengiectasia has an increased risk of malginancy when

Answer 38

in the 3rd decade of life

Question 39

ataxia telengiectasia has what kind of recurring illness

Answer 39

pneumonia and sinusitis (AFP is high)

Question 40

in what condition do B cells fail to form into plasma cells causing a deficiency of all the Ig subtypes

Answer 40

combined variable immunodeficiency

Question 41

a risk of EBV associated lymphoma is seen in

Answer 41

CVID

Question 42

recurrent HSV and VZV infections are common in

Answer 42

CVID

Question 43

IgM will not class switch to IgG due to a missing signal from t and b cells in what syndrome

Answer 43

HyperIgM Syndrome

Question 44

patients with HyperIgM syndrome have wat kind of infections

Answer 44

PNA, sinusitis and OM

Question 45

tx for hyperIgM is

Answer 45

IVIG

Question 46

how to test for b cell deficiency

Answer 46

obtain titers

Question 47

condition where there are no b cells so no immunoglobulins

Answer 47

x linked agammaglobulinemia

Question 48

when you see b cell, think of what kind of infection

Answer 48

bacterial

Question 49

ch50 is a great test to tell between XLA agammaglbulinemia and C1-C4 esterase deficiency how?

Answer 49

CH50 is nl in XLA and low in C1-C4 complement deficiency

Question 50

this condition: - presents at 6 month - only in boys - recurrent bacterial infections (encapsulated) - lack of B cells ( aka no Ig's ) - High T cells

Answer 50

X linked agammaglobulinemia

Question 51

tx for XLA

Answer 51

IVIG, abx ppx or BMT is curative

Question 52

transient hypogammaglobulinemia of infance has low what

Answer 52

IgG and IgA, gets better by age 3-6

Question 53

eosinophils high, eczema and high IgEis

Answer 53

Hyper IgE syndrome

Question 54

delayed shedding of primary dentition is seen in

Answer 54

Hyper IgE

Question 55

impaired neutrophil chemotaxisi ( aka no erythema at infection sites) is seen in what condition

Answer 55

Hyper IgE

Question 56

which complement deficiency is related to herditary angioededma

Answer 56

C1 esterase deficiency

Question 57

neutropenia, oculocutaneous albinism, low platelets and recurrent indection with staff, what is the confition

Answer 57

chedik higashi syndrome

Question 58

pancreatic insufficiecny + pancytopneia

Answer 58

schwachman diamond syndrome

Question 59

pure red cell aplpasia (only red cell line affected) + triphalngeal thumb+macrocytosis

Answer 59

diamond blacfan anemia