Amino acids Flashcards
(27 cards)
New 2 AA
Selenocysteine
Pyrrolysine
lowest and highest mol weight of AA
74 (glycine) & 204 (Tryptophan)
all AA except glycine are
Optically active
atleast 2 stereoisomer
Alpha AA
L-form “S”
Is L OR D from of AA more common
L-form “S”
where is D found
D form “R “- peptidoglycan
D& L mix -Gramicidin and
Valinomycin
exception to L-form “S”
L-cys”R”
which AA has more than 2 steroisomers.. how many?
Threonine and Isoleucine .. 4
Nature of AAs
table in note
properties of Glycine
smallest,Optically inactive, silk fibroin, Collagen
which AA is the precursor for Heme (S- amino levulinic acid)
Glycine
which AA is Inhibitory neurotransmmitter opens cl -channels
Glycine
which AA Occupies Max area on Ramachandran plot and why?
Glycine.. due to minimum steric hinderance
which AA plays role in glucose alanine cycle b/w muscle and liver
Alanine
which are the branched chain AA
valine, isoleucine, leucine
How many chiral C does isoleucine have and position
2, 2S , 3S
Maple syrup urine disease
non-funcional enzyme branched chain-alpha-ketoacid dehydrogenase
AA precursor of (SAM)-S-Adenosyl methionine
METHIONINE
is METHIONINE polar or non polar.
special feature
forms what?
Non-polar, S containing
(SAM)-S-Adenosyl methionine precursor
Legumes all def in methionine
Legumes all defieceint in which AA
METHIONINE
PROLINE, structure , ramachandran plot
aliphatic, cyclic structure
least area on Ramchandran plot due to hinderance at phi angle
Disrupts alpha helix due to cyclic structure but presents in B turn and collagen helix
Aromatic AA
Phe, Tyr, trp, His
What is the precursor for tyrosine & phenyl propanoids
Phe
phenylketonuria
Automal recessive
absence of phenyl alanine hydroxylase
Tyrosine is precursor for
L-DOPA
Dopamine
Catecholamines (epinephrine)
Thyroxine, melanin
Morphine
