Amiodarone Flashcards
1
Q
Class
A
Antiarrhythmic agent
2
Q
Mech of action
A
Multiple effects of sodium, potassium and calcium channels
Prolongs action potential, refractory period
Ventricular automaticity (potassium channel blockade
Slows membrane depolarization and impulse conduction (sodium channel blockade)
Negative chronotropic activity in Nodal tissue, rate reduction, and anti-sympathetic activity (calcium channel and B blockade)
Dilates coronary artery’s due to calcium channel and alpha-adrenergic blocking action.
