Mag Sulfate

Question 1

Class

Answer 1

Electrolyte

Tocolytic

Question 2

Mechanism of action

Answer 2

Pharmacological: second most plentiful intracellular cation; Essential to enhance intracellular potassium replenishment and activity of many enzymes; important role in neurochemical transmission and muscular excitability (May decrease acetylcholine released by nerve impulses)
Decreases my cardio irritability and neuromuscular irritability

Clinical: cardiac-reduces ventricular irritability, especially when associate it with hypo magnesemia, Inhibition of muscular excitability

Question 3

Indications

Answer 3

Torsades de pointes 
Hypomagnesemia
Preterm labor
Pregnancy induced hypertension( PIH, toxemia of pregnancy, preeclampsia and or eclampsia
Hyper active airway – severe asthma

Question 4

Contraindications

Answer 4

Hyper magnesemia

Used cautiously in patients with impaired renal function and pre-existing heart blocks

Precautions: caution when use with barbiturates, narcotics, or other hypnotics in conjunction with magnesium sulfate do to addictive sensual depressive effects of magnesium