Analgesia in Dentistry Flashcards

1
Q

When should we start systemic analgesics?

A

Before the LA wears off

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2
Q

Name examples of NSAIDs (3)

A
  1. Aspirin
  2. Ibuprofen
  3. Diclofenac
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3
Q

What was aspirin used for dentally

A

Dental + TMJ pain

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4
Q

What drug is used more commonly in dentistry now?

A

Ibuprofen

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5
Q

List some aspirin properties (4)

A
  1. Analgesic
  2. Antipyretic
    - Reduces elevated temp in fever
  3. Anti-inflammatory
    - Reduces redness + swelling as well as pain at the site of injury
  4. Anti-platelet
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6
Q

Function of prostaglandins

A

They don’t cause pain directly but they sensitise the tissues to other inflammatory products

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7
Q

Mechanism of action for aspirin

A
  1. Reduces production of protaglandins
  2. Inhibits COX1+2
    - COX1 inhibition reduces platelet aggregation
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8
Q

List some adverse effects of aspirin (4)

A
  1. GIT problems
    - Mostly on mucosal lining of stomach
    - Care taken when prescribing for pts with ulcers/gastro-oesophageal reflux
  2. Hypersensitivity
    - Acute bronchospasm
    - Minor skin rashes
    - Care when prescribing to asthmatics
  3. Overdose
    - Hyperventilation
    - Vasodilation + sweating
    - Tinnitus + deafness
  4. Aspirin burns - mucosal
    - When aspirin is applied locally to oral mucosa this results in chemical burns
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9
Q

What groups to avoid for aspirin?

A
  1. Peptic ulceration
  2. Epigastric pain
  3. Bleeding abnormalities
  4. Anticoagulants
  5. Pregnancy/breastfeeding
    - Risk of haemorrhage + jaundice in baby
  6. Patients on steroids
  7. Renal/hepatic impairment
  8. Children under 16
  9. Taking other NSAIDs
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10
Q

What drug should not be prescribed post extraction/minor oral surgery?

A

Aspirin

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11
Q

What drug should be prescribed post operatively?

A

Ibuprofen

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12
Q

Aspirin dose for mild/moderate odontogenic or inflammatory pain?

A

5 day regimen

40 tablets 300mg
2 tablets 4x daily after food

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13
Q

NSAID prescription for a hx of previous or active peptic ulcer disease for tx of odontogenic pain?

A

5 day regimen to prevent gastric problems

Lansoprazole capsules
15mg
5 capsules 1 daily

OR

Gastro-resistant omeprazole capsules
20mg
5 capsules 1 daily

NEITHER are licensed for children

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14
Q

Ibuprofen dose for mild/moderate odontogenic post op or inflammatory pain?

A

5 day regimen

400mg Ibuprofen
20 tablets
1 tablet 4x daily after food

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15
Q

Whats the max dose of ibuprofen in adults?

A

2.4g

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16
Q

List some ibuprofen potential drug interactions

A
  1. ACE inhibitors
  2. Antibiotics
  3. Anticoagulants
  4. Antidepressants
  5. Beta blockers
  6. Ca channel blockers
  7. Ciclosporin
17
Q

List some symptoms of ibuprofen overdose (3)

A
  1. Nausea
  2. Vomiting
  3. Tinnitus
18
Q

How do NSAIDs work?

A

Inhibit COX and so reduce prostaglandins (which sensitise other tissues to other inflammatory mediators, resulting in pain)

19
Q

What are non selective NSAIDS contraindicated in?

A

Patients with a hx of peptic ulceration

20
Q

How does paracetamol differ to ibuprofen and aspirin?

A

Little or no anti-inflammatory action

21
Q

Paracetamol dose for mild.moderate odontogenic or post op pain

A

500mg tablets
40 tablets
2 tablets 4x daily

22
Q

Where do opioid analgesics act?

A

On the spinal cord

They are relatively ineffective in dental pain

23
Q

What are some opioid analgesics problems? (2)

A
  1. Dependence
    - Withdrawal leads to cravings
  2. Tolerance
    - Keeps increasing
24
Q

Most common opioid side effects (3)

A
  1. Nausea
  2. Vomiting
  3. Drowsiness
25
Q

What group of people should we be cautious for opioids? (4)

A
  1. Hypotension
  2. Hypothyroidism
  3. Asthma
  4. Pregnancy
26
Q

When should dihyrocodeine never be prescibed?

A

In patients with raised intracranial pressure/suspected head injury

27
Q

Why do we avoid dihydrocodeine?

A

Due to side effects of nausea + vomiting its of little value for dental pain

It’s not very effective for post-op dental pain

28
Q

Whats the main drug used for trigeminal neuralgia?

A

Carbamazepine