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Flashcards in Anemia Deck (3)
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1
Q

Hemoglobinopathies

A

inherited disorders that affect structure, function and production of hemoglobin
eg: sickle cell disease
Thalassemia

2
Q

Patient at risk for hemoglobin electrophoresis

A

African
Mediterranean
Middle Eastern
southeast Asian
West Indian descent
or
If low MCV/MCH

3
Q

Hemoglobinopathies

A

AA hemoglobin = Normal hemoglobin
AS hemoglobin = sickle cell trait (heterozygous)
SS hemoglobin = sickle cell disease (homozygous)

AA hemoglobin in conjunction with a microcytic RBC and normal ferritin level suggests: Alpha Thalassemia

Decreased levels of HbA1, Increased levels of HbA2 and hemoglobin F = beta thalassemia