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Flashcards in anemia drugs Deck (10):
1

treatment for iron def

ferrous sulfate

ferrous gluconate

ferrous fumarate 

iron dextran = parenteral iron 

2

deferoxamine

treatment for acute iron tox - it chelates iron 

3

cyanocobalamin

therapeutic vit B12

nasal, oral, parenterally (this is how its usually given)

 prefered for long term use becuase it doesnt cause antibody response like in other agents

4

hydroxocobalmin

therapeutic vit B12

higly protein bound and remians in circ longer

some patienst produce antibodies to this bound to proteins in the blood (transcobalamin2)

5

treatment for normocytic anemia

erythropoietin 

6

treatment for folic acid def

folic acid

leucovorin 

7

epoetin alpha (erythorpoeitin)

stimulates red cell production, reticulocyte release

used in anemia pateints with chronic renal failure,HIV infection, or cancer patients getting chemo

adverse effects = hypertension, thrombosis

8

filgrastim (G-CSF)

use in a stem cell donor to mobilize stem cells for harvest

stimulates granulocytes

prevents and treats cytotoxic chemotherapy related neutropeai

reduces time to engraftment after autologous stem cell transplant

9

sargramostim (GM-CSF)

uses similar to filgrastim (G-CSF)

adverse effects are common: fever, malaise, arthralgia, myalgia, capillary leak syndrome (peripheral edema, pleural and pericardial effusions)

10

oprelvekin (IL-11)

promotes megakaryopoiesis

increases platlet numbers

used in pateinst recieaving cytotoxic chemo