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Hematologie > Anemie > Flashcards

Anemie Flashcards

1
Q

Sikkelcelanemie
Basaal defect:
Eiwitniveau:
Klinische gevolgen:

A

Basaal defect: mutatie b-ketens
Eiwitniveau: polymerisatie deoxy-HbS
Klinische gevolgen: obstructie microcirculatie

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2
Q

Betathalassemie
Basaal defect:
Eiwitniveau:
Klinische gevolgen:

A

Basaal defect: synthese b-ketens
Eiwitniveau: overschot vrije a-ketens
Klinische gevolgen: intramedullaire hemolyse

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3
Q

Alfa-thalassemie
Basaal defect:
Eiwitniveau:
Klinische gevolgen:

A

Basaal defect: synthese a-ketens
Eiwitniveau: overschot vrije b-ketens
Klinische gevolgen: bij HbH ziekte verhoogde afbraak in milt

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4
Q

Wat is een pancytopenie?

A

Te weinig erytrocyten, leukocyten en trombocyten

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5
Q

IJzergebrek micro, normo of macro?

A

Microcytair

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6
Q

Thalassemie micro, normo of macro?

A

Microcytair

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7
Q

Beenmerkziekte micro, normo of macro?

A

Normocytair

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8
Q

Hemoglobinopathie micro, normo of macro?

A

Normocytair

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9
Q

Gecombineerde deficiëntie micro, normo of macro?

A

Normocytair

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10
Q

Vitamine B12 tekort micro, normo of macro?

A

Macrocytair

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11
Q

Foliumzuur tekort micro, normo of macro?

A

Macrocytair

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12
Q

Myelodysplasie micro, normo of macro?

A

Macrocytair

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13
Q

Reticulocytose micro, normo of macro?

A

Macrocytair

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Hematologie (7 decks)

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