Angina, blood clots... Flashcards

(53 cards)

1
Q

Nitroglycerin adverse effects 2 you don’t know

A

Throbbing headache, Syncope

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2
Q

Nitroglycerin contraindications 3 you don’t know

A

Pericardial tamponade, constrictive pericarditis, glaucoma

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3
Q

Indications for Atenolol 4

A

HF, HTN, Stable angina, Post acute MI

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4
Q

Mechanism of action for atenolol

A

beta-adrenergic antagonist slows hr and contraactillity

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5
Q

CCB Indications 2

A

HTN, Coronary art disease

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6
Q

ccb mechanism of action

A

blocks calcium ch in smooth muscles and cardiac muscles, dilates coronary arts.

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7
Q

CCB Adverse effect 1

A

P edema

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8
Q

Atenolol contraindications

A

advanced AV heart block, decompensated HF

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9
Q

Heparin class 2

A

anticoagulant, indirect thrombin inhibitor

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10
Q

Heparin mechanism of action

A

binds to antithrombin lll, inhibits thrombin inactivates factor Xa

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11
Q

Heparin adverse effects 4

A

HIT, possible hypersensitivity because of animal source, osteoporosis if longer than 30 days. Skin lesions

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12
Q

Contraindications for anticoagulants

A

active internal bleeding, severe HTN, recent trauma, inter-cranial hem, bacterial endocarditis, hit

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13
Q

Heparin indications 5

A

Thromboembolic disease, DVT, unstable angina, MI, PE.

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14
Q

Warfarin- 3 things

A

Most popular, vit K antagonist avoid vit K War

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15
Q

Warfarin indications

A

Long term prophylaxis of arterial thromboembolism, Prevention of stroke/MI/AFIB, prophylaxis of DVT, PE, surgery, prosthetic heart valves.

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16
Q

Dabigatran Mechanism of action

A

direct thrombin inhib.

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17
Q

Dabigatran indications

A

non-valv A-fib

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18
Q

Warfarin therapeutic effect

A

3-4 days

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19
Q

What drugs have BBW?

A

Atenolol, Warfarin- Don’t stop immediately.

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20
Q

Warfarin AE

A

Purple toe syndrom

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21
Q

Look up labs

A

for warfarin and heparin

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22
Q

Warfarin Contraindication

A

Hepatic impairment and sever CKD.

23
Q

Dabigatran contraindications 2

A

mechanical heart valves, sever kidney disease.

24
Q

Digoxin class

A

Intropic, cardiac glycoside.

25
Why use Digoxin ?
Patients not responding to Ace inhib. and need a better cardiac output.
26
MA Digoxin
Inhibits NA+K+ATpase pump
27
Digoxin AE 6
Dysrhythmias, hypokalemia, Hypercalcimia, renal problems, halos, malaise
28
Digoxin Avoid
potassium
29
When to hold meds digoxin
heart rate below 60
30
Contraindications for digoxin 3
beers list, ace inhib spirolactone, K,
31
Alteplase class
Thromobliytic, fibrinolytic
32
Alteplase MA
Converts plasminogen to plasmin
33
Alteplase contraindications
Intracranianial hemorrhage, cerebral legions, intracranial neoplasam, hemorrhagic stroke, dissection of aorta, active bleeding.
34
aminocaproic acid class
Hemostatic, shortening bleeding time, antifibrinolytic,
35
aminocaproic acid MA and one AE
Clots blood. Blocks sites on plasminogen and plasmin aprevents digestion of fibrin clot. can irritate veins.
36
Nursing considerations for aminocaproic acid
Check IV site for thrombophletis, monitor CPK activity. report fever and discolored urine,
37
Hemostatics what system?
Urinary
38
Acetylsilic acid class and how long can it last?
Antiplatelet one week.
39
Acetylsilic acid indications
MI prophylaxis, suspected coronary thrombosis before ER
40
MA for Acetylsilic acid
binds to cyclooxygenase (COX) enzyme in platelets, inhibits platelet aggregation.
41
AE of Acetylsilic acid
``` Hypersensitivity bronchospasm, laryngeal edema, anaphylaxis stomach irritation GI bleed thrombocytopenia Liver/kidney toxicity tinnitus ```
42
thrombocytopenia considerations 2
hearing and renal function
43
Contraindications for Acetylsalic acid
allergy/nasal polyps/asthma/ chronic rhinitis, acute bronco spasms, Vit K deficiency
44
the ks three
Asprin-Can't take if you have a VIT K deficiency warfarrin -avoid VIT K Digoxin- potassium reduces effects
45
Clopidogrel Class
Antiplatelet, ADP receptor blocker
46
Clopidogrel indication
prevention of arterial thromboembolism
47
Clopidogrel MA
Inhibits ADP receptors on platelets | prolongs bleeding time irreversibly inhibits aggregation Can last several days! BLEEDING ISSUES-Not many AE
48
Abciximab class
Antiplatelet, glycoprotein llbllla inhibitor.
49
Abciximab indications
IV only. coronary angioplasty procedures, revascularization of arts.
50
Abciximab MA
Binds to GP llb/llla receptor sites on platelets | Prevents fibrinogen von willebrand factor and other procoagulants from being activated.
51
Labs for warfarrin
PT (prothrombin time) and INR
52
Teaching for digoxin 3 others
report vision, saftey margin, long half life. and the others
53
conditions that thrombolytics are used for WHAT IS IT NOT USED FOR
MI, Stroke, declotting centeral lines, NOT FOR ANGINA