ANNA Flashcards
(6 cards)
bacteriostatic?
inhibits / stops bacterial growth
bactericidal?
kills cells, but no lysis or cell rupture
bacteriolytic?
induces killing by cell lysis, releasing cytoplasmic contents
what makes a good antibiotic?
Broad spectrum or narrow spectrum
Low toxicity
Good bioavailability
Minimal contradictions – safe in pregnancy, poor renal function, newborns/infants
Long half life
Available intravenously and orally
combination therapy - synergy?
When two antimicrobial agents are combined together and they elicit a greater antimicrobial activity than the sum of the two antimicrobial agents individually
combination therapy - antagonism?
When two antimicrobial agents are combined together and they elicit a lower antimicrobial activity than the sum of the two antimicrobial agents individually