ANS Flashcards

1
Q

Botulinum toxin

A

Inhibits release of acetylcholine from presynaptic neuron by inhibiting calcium channel

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2
Q

Which type of botulinum toxin is used as drugs

A

Type A toxin»»type B

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3
Q

Type A botulinum toxin e.g.

A

Onabotulinum toxin A(botox),
Abobotulinum toxin A(dysport),
Incobotulinum toxin A

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4
Q

Antagonist of Nn receptors

A

Ganglionic blockers
E.g- hexamethoneum
Trimethaphan

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5
Q

Nm receptors antagonist

A

Non depolarising muscle relaxant (NDMR)
E.g - tubo curare
Atra curium
Ve curonium

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6
Q

Predominant muscarinic receptor in brain

A

M1

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7
Q

Drug for alzheimer and why

A

Cholinergic drugs—> inc. Ach —-> acts on hippocampus
Ach–> inc. memory and cognition

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8
Q

Cholinergic or anti cholinergic drugs in parkinson’s disease,why

A

Anti cholinergic drugs.

Ach —> acts on basal ganglia –>
dec. Dopamine

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9
Q

M1 receptor agonist

A

OXOTREMORINE (inc. HCl)

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10
Q

M1 receptor antagonist

A

PIREN ZEPINE,
TELEN ZEPINE,

dec. HCl , therefore given in PEPTIC ULCER

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11
Q

Which muscarinic receptor antagonist are given in PEPTIC ULCER and why

A

M1 receptor antagonist,
PIREN ZEPINE
TELEN ZEPINE,

dec. HCl

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12
Q

M2 receptor is located in

A

Heart

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13
Q

M2 receptor agonist

A

METH CHOLINE

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14
Q

M3 receptor function

A

Vasodilation - blood vessels
Contraction -smooth muscle

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15
Q

M3 receptor agonist

A

BETHAN ECOL
inc. smooth muscle contraction

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16
Q

M3 receptor antagonist

A

SOLE FENA CIN,
DARE FENA CIN,

relaxes smooth muscle

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17
Q

Direct acting cholinergic drugs - esters e.g.

A

chol in all

A- Acetylcholine
B- BETHANE CHOL
C- CARBA CHOL
M- METHA CHOLINE

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18
Q

Specific Aplha 1 agonist

A

PHENYL EPHRINE

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19
Q

Specific Aplha 2 agonist

A

COLNIDINE

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20
Q

Specific Aplha 1 antagonist

A

PRA ZO SIN

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21
Q

Specific Aplha 2 antagonist

A

YO HIM BINE

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22
Q

Non specific Alpha agonist

A

EPINEPHRINE,
NOR EPINEPHRINE

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23
Q

Non specific Alpha antagonist

A

PHENOXY BENZAMINE,
PHENYO LAMINE

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24
Q

Specific beta 1 agonist

A

DO BUTAMINE

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25
Specific beta 1 antagonist
ATENO LOL METO PRO LOL
26
Specific beta 2 agonist
SAL BUTA MOL, RITO DRINE
27
Specific beta 2 antagonist
BUTAX AMINE
28
Specific beta 3 agonist
MIRA BEGRON
29
Non specific beta agonist
ISO PRENA LIN
30
Non specific beta antagonist
PRO PRANO LOL
31
DOC cardiogenic shock
Nor epinephrine , Dopamine
32
DOC in vasodilatory shock
Nor epinephrine , Dopamine
33
Epinephrine acts on which sympathetic receptors
Alpha 1, Alpha 2, Beta 1, Beta 3
34
Epinephrine is used in
ABCD A- Anaphylaxis B- Brittle asthma C- Cardiac Arrest D- During/along with local anaesthetic
35
Epinephrine acts on which sympathetic receptors
Alpha 1,2, Beta 1,2,3
36
Dopamine acts on which sympathetic receptors
D1-D2, Alpha 1 2 Beta 1-3
37
DOC in oliguria/acute renal failure
DOPAMINE (Low dose 1-2 micro g/kg/min. coz acts on D1
38
Phenylephrine
1- selective Alpha 1 agonist 2-DOC in hypotension in spinal anesthesia 3- DOC in hypotension in aortic dissection
39
MIDODRINE
DOC in postural hypotension
40
DOC in postural hypotension
MI DO DRINE
41
DOC in hypotension in spinal anesthesia
PHENYL EPHRINE
42
DOC in hypotension in aortic dissection
PHENYL EPHRINE
43
Topical nasal drops
OXY META ZOLINE, XYLO META ZOLINE, NAPHA ZOLINE, PHENYLEPHRINE
44
Oral nasal decongestants
Phenylephrine Ephedrine Pseudophedrine
45
Tocolytics/ uterine relaxant drugs
RITO DRINE ISO XEU PRINE
46
Drug used in treatment of overactive bladder
MIRA BE GRON, Beta 3 agonist
47
DOC in narcolepsy
MODA FINIL, TIPRO LISANT, SOLRI AM FETOL,
48
DOC in obstructive sleep apnea
MOD FINIL
49
DOC in adhd
METHYL PHENI DATE
50
Drug used to increase attention span
METHYL PHENI DATE
51
DOC in hypotension in pregnancy
EPHEDRINE
52
Alpha 2a agonist
CD TAG C- Clonidine D- Dex mede to midine T- Ti zani dine A- Alpha methyl dopa G- Guanfacine,Guanbenz
53
DOC in: 1- pregnancy induced hypertension 2- chronic htn in pregnancy
1- Labetalol 2- Alpha methyl dopa
54
Non selective Alpha blockers,non competative + irreversible blockers
PHEN OXY BENZAMINE
55
Non selective Alpha blockers, competative+ reversible blockers
PHEN TO LAMINE TOLA ZO LINE CHLOR PRO MAZINE ERGO TAMINE
56
DOC in pheochromocytoma
PHENOXY BENZAMINE (non selective Alpha blockers)
57
Alpha 1 A blockers
Prazosin, Terazosin, Doxazosin, Alfuzosin, (all ends with zosin)
58
DOC in postural hypotension
MI DO DRINE
59
BPH +HTN
Prazosin
60
DOC for glaucoma
PGF2 alpha