Autcoids Flashcards

1
Q

Highly sedative anti histaminics

A

PRO METHA ZINE,
DI PHEN HYDRA MINE,
HYDROXY ZINE,
DOXE PIN,
DOXYL AMINE

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2
Q

Anti histaminic with transdermal patch

A

Diphenhydramine

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3
Q

Anti histaminics ,used in
Motion sickness,
Drug induced parkinson’s disease

A

Pronethazine,
Diphenhydramine

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4
Q

Anti histaminics which can also be used as local anaesthetic

A

Promethazine,
Diphenhydramine

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5
Q

Anti histaminics with maximum anti pruritic effect

A

Hydroxyzine

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6
Q

Anti histaminic which is also a tricyclic antidepressants

A

Doxepin

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7
Q

Antihistamine
DOC in morning sickness

A

Doxylamine

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8
Q

Moderately sedative antihistamine

A

Cycli zine,
Mecli zine,
Cinnari zine,
Cypro heptadine,
Pheni ramine

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9
Q

Antihistamine good in sea sickness

A

Cycli zine,
Mecli zine,
Cinnari zine

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10
Q

Antihistamine + anti serotonin

A

Cypro heptadine

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11
Q

Least sedative antihistamine

A

CHLOR pheni ramine,
Clemastine,
Tirolidine

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12
Q

DOC in Anaphylaxis

A

I/m adrenaline 0.5 ml of 1:1000

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13
Q

2nd gen antihistamine

A

Fexo fenadine,
Cetrizine,
Levo cetrizine,
Loratidine,
Rupatidine,

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14
Q

Banned 2nd gen antihistamine

A

Terfinadine,
Astemizole

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15
Q

2nd gen antihistamine also PAF inhibitor

A

Rupatidine

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16
Q

Topical 2nd gen antihistamine

A

ALOKA
A- Aze lastine
L- levo car bastine
O- Olopa tidine
K- Keto tifen
A- Alcaf tadine

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17
Q

H2 blockers

A

Cime tidine,
Rani tidine,
Famo tidine,
Roxa tidine,
Niza tidine,
Lafu tidine,

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18
Q

H2 blockers which causes
Gynecomastia,
Menstrual irregulation

A

Cime tidine

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19
Q

H2 blockers which can cause
Galactorrhoea

A

Cime tidine

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20
Q

H2 blockers - max. CYP inhibitor

A

Cime tidine

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21
Q

Only drug for H3 receptor

A

Tipro lisant (pito lisant)
H3 INVERSE ANTAGONIST
INC. HISTAMINIC RELEASE

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22
Q

Tipro lisant can be used to treat

A

Narcolepsy

23
Q

DOC in narcolepsy

A

Moda finil

24
Q

No. Of receptors of serotonin

A

7,
5HT1-5HT7

25
Only ionotropic receptor of serotonin
5HT3
26
5HT1-ttpe and location
Gi, Brain
27
Subtypes of 5Ht1 receptor
5HT1A,B,D,F
28
5HT1A partial agonist
Buspirone
29
Specific 5ht1B/D agonist
Triptans
30
DOC in acute attack of migraine
Triptans
31
Name some Triptans
SER FANZ (all ends with Triptan) S- Sunatriptan E- Eletriptan R- Rizatriptan F-Frovatriptan A-Almotriptan N- Naratriptan Z- Zolmitriptan
32
Triptan which can be given by all routes iv,im, rectal, transdermal and nasal spray
Sunatriptan
33
Most effective Triptan
Eletriptan
34
Fastest acting Triptan
Rizatriptan
35
2nd most effective Triptan
Rizatriptan
36
Longest acting Triptan
Frovatriptan
37
Triptan with best oral absorption
Naratriptan
38
Triptan which can be given as nasal spray
Zolmitriptan
39
Non specific 5HT1 agonist
Ergotamine
40
Triptan/ergotamine, Emetogenic/ anti emetic
Triptan -anti emetic Ergotamine - emetogenic
41
Side effects of Triptan, ergotamine
HERD H- Hypertension, coronary vasospasm E- erythromelalgia R- raynauds disease D- dry gangrene of fingers
42
Triptan, ergotamine are C/I in
CAD(coronary artery disease) patients -can cause MI and angina
43
Treatment of ergotism
Nitroprusside - vasodilator
44
DOC for prolactinoma
Cabergoline
45
DOC in prolactinoma+ pregnancy
Bromocriptine - dopamine agonist
46
Which ergots cause cardiac valvular fibrosis
Pergolide, Cabergoline
47
Ergots which causes retroperitoneal fibrosis
Methysergide
48
Inflammatory fibrosis by ergots
Cardiac valvular fibrosis, Retroperitoneal fibrosis, Pleural fibrosis, Peritoneal fibrosis
49
T/t of mild migraine
NSAIDS along with caffeine PAIND P- PCM A- Aspirin I- Indomethacin N- Naproxen D- Diclofenac
50
T/t Moderate/severe migraine
Triptan>> ergotamine
51
Migraine+ Triptan resistant+ heart patient ---drug preferred
Opioids like Butorphanol, Pethidine, Morphine
52
Drugs to control migraine aura
D2 antagonist like Domperidone, Metoclopramide, Antipsychotic like Chlorpromazine, Prochlorperazine
53
T/t migraine in pregnancy
Safest drug PCM
54