Antenatal and Prenatal Pharm - Fitz Flashcards Preview

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Flashcards in Antenatal and Prenatal Pharm - Fitz Deck (38)
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31

Any drug that is cleared _____ must be a reduced dose in kids under 6 months

Renally

32

Sulfamethoxazole in infants

CONTRAINDICATED -- kernicterus (inhibits ability to clear bilirubin in kids)

33

Chloramphenicol in infants

CONTRAINDICATED - gray baby syndrome (V/D, circulatory collapse, abdominal distention, dusky gray color

34

Class B antibiotics (pregnancy) - ok to use

Cephalosporins, Penicillins

35

Class C antibiotics (pregnancy)

Risk?

Fluroroquinolones, Trimethoprim

Birth defects

36

Class D antibiotics (pregnancy)

Risk?

Tetracyclines

Fatty liver (mother) hepatotoxicity

37

Antibiotics contraindicated in children...

Under 8?
Under 18?

Under 18 = Fluroroquinolones (floxacin) (cartilage erosion)

Under 8 = Tetracyclines (bone and teeth deposits) AND Fluoroquinolones

38

Trimethoprim -- why contraindicated in pregnancy?

DHFR inhibitor = deficient folate = BIRTH DEFECTS (months 2 and 3) -- CV defects and oral clefts