Early Pregnancy, Ectopic, RH - Moulton Flashcards

(29 cards)

1
Q

Define the 3 trimesters by weeks

A
1 = 1 - 13.6
2 = 14 - 27.6
3 = 28 - 42
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2
Q
Abortion = before week \_\_\_
Preterm = before week \_\_\_
Post-term = after week \_\_\_
A

20
37
42

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3
Q

***How does hCG rise in pregnancy?

A

Doubles every 2 days, peaks at 10 weeks at 100,000

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4
Q

***At what point will a gestational sac be visible on ultrasound?

What is this called?

A

hCG = 1500-2000

Discriminatory level

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5
Q

At what point is a spontaneous abortion unlikely?

A

8 weeks, appropriate size, cardiac activity seen

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6
Q

Most common cause of spontaneous abortions

Most common one?
Most common CLASS?

A

Chromosome abnormalities

Turner (45 XO)

Trisomies (16 esp.)

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7
Q

“Types” of abortion…

  • Vaginal bleeding, closed cervix
  • Vaginal bleeding, cervix partially dilated
  • Vaginal bleeding, cramping lower abdominal pain w/ dilated cervix
A

Threatened

Inevitable

Incomplete

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8
Q

“Types” of abortion…

  • Passage of all products w/ closed cervix, resolution of all symptoms
  • Fetus has expired, still in uterus,
A

Complete

Missed

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9
Q

“Types” of abortion…

  • Fever, cervical tenderness, purulent discharge, retained POC
  • Gestational sac, no embryo
A

Septic (endometritis)

Blighted ovum

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10
Q

Treatment of cervical incompetence

A

Cervical cerclage

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11
Q

Testing for APA syndrome (3)

Treatment?

A
  • Lupus anticoagulant
  • Anticardiolipin Ab
  • Anti-B2-glycoprotein 1 Abs

Prophylactic heparin and aspirin

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12
Q

Most common cause of maternal death in 1st trimester

A

Ectopic pregnancy

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13
Q

Ectopic pregnancy - classic triad

A
  • Missed menstrual cycle
  • Bleeding later
  • Lower abdominal pain
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14
Q

Ultrasound finding = thickened endometrial stripe (Arias-Stella reaction)

A

Ectopic pregnancy

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15
Q

Ultrasound finding = fluid in cul de sac…what is it?

A

BLOOD - ruptured ectopic pregnancy

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16
Q

Treatment of ectopic pregnancy

How to know if it’s working?

A

Methotrexate

hCG drops by 15% from day 4 to day 7

17
Q

5 types of surgery for ectopic pregnancy

A
  • Laparotomy (if unstable)
  • Laparoscopy (if stable)
  • Salpingectomy (remove tube)
  • Salpingostomy (leave open)
  • Salpingotomy (close incision)
18
Q

Describe RH sensitization in pregnancy

Treatment?

A

Rh- mom, Rh+ baby, anti-Rh IgG’s cross placenta and cause hemolysis in baby

Prophylactic RhoGAM

19
Q

What is required for RH sensitization to occur? How?

A
  1. 1 mL of fetal blood to get into the mother

- ANY cause of trauma, placental issue, etc.

20
Q

If genetic testing of parents shows that the baby has a risk of developing RH hemolysis from mom, do what?

A

Amniocentesis - fetal antigen testing, bilirubin levels (looking for signs of hemolysis)

21
Q

Signs of fetal hydrops on ultrasound (4)

A
  • Ascites
  • Pleural effusion
  • Pericardial effusion
  • Skin or scalp edema
22
Q

TODAY, how to best determine if fetal RH hemolysis is occurring in baby? Explain.

A

Fetal MCA peak systolic velocity

- If getting anemic from hemolysis, will pump faster to compensate, will be detected by doppler of MCA

23
Q

Treating baby with fetal hydrops

A

Transfusion of O- blood (umbilical vein or other)

24
Q

Nonstress testing

A

Monitor fetal heart rate accelerations and decelerations to fully assess the fetal sleep-wake cycle

25
Girl comes in with minimal vaginal bleeding and cramping sensation. Pregnant, blood in uterus, cervix is closed. AB negative. Dx? Plan? (3)
Threatened abortion - SAB precautions - Follow up in 1 week - RhoGAM (bleeding + pregnancy + Rh-)
26
Woman w/ previous abortions, mild cramping. Positive pregnancy test. hCG 1000. Ultrasound shows nothing. Potential Dx? (2) Plan? Why?
Normal IUP or SAB Repeat testing in 2 days -- hCG will be in discriminatory zone
27
Contraindications of methotrexate for ectopic pregnancy (10)
- Breastfeeding - Immunodeficiency - Alcoholism or liver disease - Blood disease - Sensitivity to MTX - Active pulmonary disease - Peptic ulcer disease - Large gestational sac - Embryonic cardiac activity
28
MTX - MoA
Folic acid antagonist -- inhibit DNA synthesis and cell replication
29
If giving MTX and hCG is falling normally, do what? If NOT falling normally, do what? If symptomatic or bHCG starts rising?
Follow weekly until negative Give another dose Surgery