Antenatal - small for gestational age Flashcards

1
Q

what is small for gestational age defined as?

A

fetus that measures below the 10th centile for gestational age

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2
Q

what 2 measurements are used to assess fetal size?

A

estimated fetal weight (EFW)

fetal abdominal circumference (AC)

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3
Q

mothers have customised growth charts generated to assess the size of the fetus. what are the growth charts based on?

A

mothers ethnic group, weight, height and parity

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4
Q

what is considered to be severe small for gestational age (SGA)

A

when the fetus is below the 3rd centile for their gestational age

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5
Q

low birth weight is defined as what

A

birth weight of less than 2500g

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6
Q

what are the 2 categories of small for gestational age?

A

Constitutionally small - matching the mother and others in the family, and growing appropriately on the growth chart

fetal growth restriction aka intrauterine growth restriction - small fetus due to pathology reducing the amount of nutrients and oxygen being delivered to the fetus through the placenta

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7
Q

how can the causes of fetal growth restriction be divided into categories?

A

placenta mediated growth restriction - large head in comparison to body

non-placenta mediated growth restriction - usually due to genetic or structural abnormality and babys head is in proportion to body

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8
Q

what are some placenta mediated growth restriction causes (conditions that affect the transfer of nutrients across the placenta)

A

idiopathic

pre-eclampsia

maternal smoking

maternal alcohol

anaemia

malnutrition

infections

maternal health conditions

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9
Q

what are some non-placenta mediated growth restriction causes

A
  • genetic abnormalities
  • structural abnormalities
  • fetal infection
  • errors of metabolism
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10
Q

what are some other signs that would indicate FGR other than being SGA?

A
  • reduced amniotic fluid volume
  • abnormal doppler studies
  • reduced fetal movements
  • abnormal CTGs
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11
Q

What are some short term complications of fetal growth restriction?

A
  • fetal death or stillbirth
  • birth asphyxia
  • neonatal hypothermia
  • neonatal hypoglycaemia
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12
Q

what do growth restricted babies have a long term increased risk of?

A
  • Cardiovascular disease - HTN, coronary artery problems
  • T2DM
  • Obesity
  • Mood and behavioural problems
  • autoimmune thyroid problems
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13
Q

what are some risk factors for Small for Gestational Age?

A
  • Previous SGA baby
  • Obesity
  • Smoking
  • Diabetes
  • Existing hypertension
  • Pre-eclampsia
  • Older mother (over 35 years)
  • Multiple pregnancy
  • Low pregnancy‑associated plasma protein‑A (PAPPA)
  • Antepartum haemorrhage
  • Antiphospholipid syndrome
  • malnutrition
  • substance misuse
  • domestic violence
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14
Q

how are women assessed at the booking clinic for SGA?

A

women are assessed for risk factors for SGA and then monitored accordingly. RCOG lists major and minor risk factors

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15
Q

how are women low-risk for SGA monitored?

A

have symphysis fundal height measured at every antenatal appointment from 24 weeks onwards and this is plotted on a customised growth chart to asses the appropriate size for the individual woman.

if the SFH is less than the 10th centile women are booked for serial growth scans with umbilical artery doppler

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16
Q

when are women booked for serial growth scans with umbilical artery doppler?

A

if they have:

  • 3 or more minor risk factors
  • 1 or more major risk factors
  • issues measuring SFH
17
Q

how are women at higher risk or with SGA monitored?

A

serial ultrasound scans measuring:

  • estimated fetal weight and abdominal circumference to determine growth velocity
  • umbilical arterial pulsatility index (UA-PI) to measure flow through umbilical artery
  • amniotic fluid volume
18
Q

how is SGA managed?

A
  • Identifying those at risk of SGA
  • Aspirin is given to those at risk of pre-eclampsia
  • Treating modifiable risk factors (e.g. stop smoking)
  • Serial growth scans to monitor growth
  • Early delivery where growth is static, or there are other concerns
19
Q

when a fetus is identified as SGA, what investigations are done to identify the underlying cause?

A
  • Blood pressure and urine dipstick for pre-eclampsia
  • Uterine artery doppler scanning
  • Detailed fetal anatomy scan by fetal medicine
  • Karyotyping for chromosomal abnormalities
  • Testing for infections (e.g. toxoplasmosis, cytomegalovirus, syphilis and malaria)
20
Q

when is early delivery considered in FGR?

A

when growth is static on growth charts or any other problems such as abnormal doppler results.

reduces risk of stillbirth