anti-HHV Flashcards
1
Q
Name the 5 nucleoside analogues used for HHV treatment.
A
Aciclovir, Famciclovir, galaciclovir (oral), ganciclovir (IV) and valganciclovir (oral).
2
Q
Why is ganciclovir only given under life-threatening conditions?
A
It is toxic to bone marrow.
3
Q
Which drug treats CMV retinitis?
A
Cidofovir.
4
Q
What does foscarnet treat?
A
HSV, VZV and CMV that are resistant to nucleoside analogues. It is highly nephrotoxic and can only be given IV.
5
Q
Is aciclovir an active or pro-drug?
A
Pro-drug. Converted to active form by TK.
