inhibition of protein synthesis

Question 1

Which aminoglycoside is used for serious gram negative (coliform) infection?

Answer 1

Gentamicin. Also used for gram positive staph infection.

Question 2

Why does gentamicin need to be monitored?

Answer 2

It is given IV and is toxic. Renal and oto-toxicity is common.

Question 3

What type of infections are tetracyclines used for?

Answer 3

Broad spectrum, Used for genital tract (chlamydia) and RTI’s.

Question 4

Give 2 examples of macrolides.

Answer 4

Clarithromycin and erythromycin.

Question 5

When would you prescribe a macrolide?

Answer 5

In someone who is allergic to penicillin to treat gram positive infection.

Question 6

Which organisms are macrolides effective against?

Answer 6

Mostly gram positive and a few irregular (chlamydia, coxiella and mycoplasma).

Question 7

What is azithromycin used for?

Answer 7

Chlamydia treatment

Question 8

Name an oxazolidinone effective against MRSA infection.

Answer 8

Linezolid. Can cause bone suppression so only used in serious infections.

Question 9

Which cyclic lipopeptide is useful for MRSA and gram positive infection?

Answer 9

Daptomycin. Useful for serious MRSA infections.