Anti HTN

Question 1

Drug-induced lupus (4)

Answer 1

It's HIPP to have lupus
Hydralazine
Isoniazid
Procainamide
Penicillamine

Question 2

why do patients taking ACEi/ARBs develop hyperkalemia

Answer 2

reduced aldosterone levels–> potassium retention

Question 3

Why give ACEi in px with DM nephropathy

Answer 3

Renoprotective (decreases albumin excretion and slows progression of micro- to macroalbuminuria

Question 4

Cause of headache in px taking nitrates

Answer 4

meningeal blood vessel dilatation

Question 5

Why is Ca-dependent neurotransmission not affected by CCB?

Answer 5

CCBs affect L-type Ca channels

other fxns use N-, P- and R- type

Question 6

Drugs that cause gingival hyperplasia (4)

Answer 6

NapaCa-Pangit ng gingiVa mo
Nifedipine
Cyclosporine
Phenytoin
Verapamil

Question 7

Complex in ETC affected by cyanide

Answer 7

Complex IV

Question 8

Antidote for cyanide poisoning

Answer 8

inhaled amyl nitrite + IV sodium nitrite + IV sodium thiosulfate

Question 9

Nitrates alone

Heart rate

Answer 9

Reflex increase

Question 10

Nitrates alone

arterial pressure

Answer 10

decrease

Question 11

Nitrates alone

end-diastolic pressure

Answer 11

DECREASE

Question 12

Nitrates alone

contractility

Answer 12

reflex increase

Question 13

Nitrates alone

ejection time

Answer 13

reflex decrease

Question 14

Nitrates alone

Net myocardial oxygen requirement

Answer 14

decrease

Question 15

BB or CCB alone

heart rate

Answer 15

decrease

Question 16

BB or CCB alone

arterial pressure

Answer 16

decrease

Question 17

BB or CCB alone

end-diastolic pressure

Answer 17

increase

Question 18

BB or CCB alone

contractility

Answer 18

decrease

Question 19

BB or CCB alone

ejection time

Answer 19

decrease

Question 20

BB or CCB alone

net myocardial oxygen requirement

Answer 20

decrease

Question 21

combined BB or CCB and nitrates

heart rate

Answer 21

decrease

Question 22

combined BB or CCB and nitrates

arterial pressure

Answer 22

decrease

Question 23

combined BB or CCB and nitrates

end-diastolic pressure

Answer 23

decrease

Question 24

combined BB or CCB and nitrates

contractility

Answer 24

no effect or decrease

Question 25

combined BB or CCB and nitrates | ejection time

Answer 25

no effect

Question 26

combined BB or CCB and nitrates | net myocardial oxygen component

Answer 26

decrease

Question 27

orthopnea, PND, pulmonary congestion

Answer 27

left sided heart failure

Question 28

hepatomegaly, edema, engorded neck veins

Answer 28

right sided heart failure

Question 29

Drugs with narrow therapeutic index

Answer 29

``` WALA na Cyang PaPa, VasTeD na warfarin aminoglycosides lithium amphotericin B carbamazepine phenobarbital phenytoin vancomycin theophylline digoxin ```

Question 30

3 drug classes that increase survival in CHF

Answer 30

ACE inh Beta blockers Aldosterone antagonists ito yung iaadd mo sa loop diuretics pag CHRONIC HF

Question 31

Effects of Class I antiarrhythmics to AP duration

Answer 31

Class IA prolong Class IB shorten Class IC no change

Question 32

Class IA antiarrhytmics

Answer 32

Procainamide disopyramide quinidine

Question 33

tx for Class IA antiarhythmic toxicity

Answer 33

Sodium lactate to reverse arrythmia | pressor sympathomimetics

Question 34

Class IB antiarrhythmics

Answer 34

I Buy Mexican Tacos from Lily | IB: mexiletine, tocainide, lidocaine

Question 35

drugs that cause agranulocytosis

Answer 35

``` CCCAPPIT Me clozapine cotrimoxazole colchicine aminopyrine phenylbutazone PTU Indomethacin Tocainide Methimazole ```

Question 36

Class IC antiarrhythmics

Answer 36

Chicken ay Pagkain For Enrico | IC: Propafenone, Encainide, Flecainide

Question 37

Non-selective beta blockers

Answer 37

propanolol, timolol

Question 38

Beta1 selective blockers

Answer 38

esmolol, acebulol, betaxolol, atenolol, metoprolol

Question 39

Beta blocker with partial agonistic properties

Answer 39

pindolol, acebulol

Question 40

BB lacking local anesthetic effects

Answer 40

timolol

Question 41

BB with low lipid solubility

Answer 41

atenolol

Question 42

shortest acting BB

Answer 42

esmolol

Question 43

longest acting BB

Answer 43

nadolol

Question 44

combine a and b blockade

Answer 44

carvedilol, labetalol

Question 45

Amiodarone toxicity

Answer 45

``` pulmonary fibrosis Paresthesias Tremors thyroid dysfunction Corneal deposits skin deposits ```