Anti-lipids Medication Flashcards Preview

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Flashcards in Anti-lipids Medication Deck (3)
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1
Q

What is the mechanism of action of Statins?

A

Statins competitively inhibit 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, an enzyme involved in cholesterol synthesis, especially in the liver.

2
Q

What is a common adverse effect of statin use, especially if given in high doses?

A

Myositis, Myopathy and Rhabdomyolysis

3
Q

Which patients are at high risk of experiencing adverse effects from statin use?

A

Patients at high risk includes those with a personal or family history of muscular disorders, previous history of muscular toxicity, a high alcohol intake, renal impairment or hypothyroidism.