Antianginal Drugs

Question 1

Which drug is contraindicated in vasospastic angina?

Answer 1

Beta-blockers

Question 2

Nitrates can cause cardiotoxicity when are combined with which drug?

Answer 2

Slidenafil

Question 3

In which cases you must avoid ranolazine? Mechanism of action.

Answer 3

QT syndrome or taking drugs that ⬆️ QT
Block late inward of Na+ in cardiac myocites ▶️ ⬇️ Ca+2 accumulation ▶️ ⬇️ end diastolic pressure ▶️ improve diastolic coronary flow