Antibacterials Flashcards Preview

ID > Antibacterials > Flashcards

Flashcards in Antibacterials Deck (25):
1

B lactams

Penicillins, B lactamase inhibitors, cephalosporins, carbepenems, monobactams

2

Antimycobacterials

Isoniazid, rifampin

3

Penicillinase resistant penicillin spectrum

Nafcillin, oxacillin. Broad Gram + coverage

4

Carbapenems

Imipenem/cilastatin. Broad Gram +, -, and anaerobes.

5

Quinolone

MOA: Nuclei acid/chromatin structure inhibitors - inhibits DNA gyrase
Protype - Levofloxacin. [] dep.

6

Penicillins

MOA: Cell wall synthesis inhibitor
Prototype: penicillin G, ampicillin.
Narrow Gram + and _ coverage

7

Nucleic acid/chromatin structure inhibitors

Quinolones, metronidazole

8

Protein synthesis inhibitors

Aminoglycosides, tetracyclines, macrolides, clindamycin, oxazolidinone

9

Cephalosporins - 3rd gen

Ceftriaxone. Narrow Gram + and broad Gram - coverage.

10

Cephalosporins - 4th gen

Cefepime. Broad gram + and Gram - coverage.

11

Nitroimidazole

MOA: Nuclei acid/chromatin structure inhibitors - damages DNA
Prototype: Metronidazole
[] dep

12

Carboxy- and ureidopenicillins

Narrow Gram + and broad Gram - coverage

13

Cell wall synthesis inhibitors

B lactams, glycopeptides
(vancomycin)

14

Macrolides

MOA: Protein synthesis inhibitors, binds 50S rev
Prototype: Azithromycin. Bactericidal/bacteriostatic.

15

Natural penicillins spectrum

Penicillin G,K: Narrow gram positive coverage

16

β-lactamase inhibitors

MOA - binds penicillin-binding proteins
Prototype: clavulanic acid

17

Aminopenicillins

Ampicillin, amoxicillin. Narrow Gram + coverage, also narrow Gram - coverage.

18

Tetracyclines

MOA: Protein synthesis inhibitors, binds 30S rev
Prototype: Doxycycline. Bacteriostatic.

19

Aminoglycosides

MOA: Protein synthesis inhibitors, binds 30S irrev
Prototype: Gentamicin. [] dep.

20

Glycopeptides

MOA: inhibit cell wall synthesis
Prototype: Vancomycin

21

Antifolates

Sulfamethoxazole/trimethoprim

22

Clindamycin

MOA: Protein synthesis inhibitors, binds 50S
Prototype: clindamycin. Bacteriostatic.

23

Cephalosporins - 1st gen

Cefazolin. Broad Gram + and narrow Gram - coverage

24

Bacteriostatic antibacterials

Tetracyclines
Clindamycin
Oxazolindinone
Macrolides (primarily, variable)

25

Cephalosporins - 2nd gen

Cefuroxim - narrow Gram + and broad Gram - coverage.
Cefoxitin - anaerobes