antibacterials: MOA Flashcards
(8 cards)
1
Q
beta-lactams
A
- Inhibit bacterial cell wall synthesis
- Bactericidal
2
Q
macrolides
A
- Inhibit bacterial protein synthesis
- Bacteriostatic
3
Q
fluoroquinolones
A
- Inhibit bacterial DNA supercoiling mechanisms and promote breakage of DNA strands
- Bactericidal
4
Q
sulfonamide
A
- Inhibits sequential steps of folate synthesis
- SMX inhibits dihydropteroate synthase
- TMP inhibits dihydrofolate reductase
- Bacteriostatic
5
Q
tetracyclines
A
- Inhibit bacterial protein synthesis
- Bacteriostatic
6
Q
lincosamide
A
- Inhibit bacterial protein synthesis
- Same site of action as macrolides
- Bacteriostatic
7
Q
nitroimidazole
A
-Inhibits bacterial DNA synthesis in anaerobic
conditions
-Bactericidal
8
Q
nitrofuran
A
-Inhibits bacterial protein synthesis, DNA/RNA
synthesis, metabolism, and cell wall synthesis
-Bactericidal
“fuehrer” dominates all (inhibits everything)
