CNS 2: SE

Question 1

which cause sedation?

Answer 1

Haloperidol, antiseizures (drowsiness, fatigue, somnolence)

Question 2

which cause hypotension?

Answer 2

Haloperidol

Question 3

which cause anticholinergic effects?

Answer 3

Haloperidol (+tachycardia)
Olanzapine
both cause: Blurred vision, dry mouth,
constipation, urinary retention, tachycardia

Question 4

which cause movement disorders?

Answer 4

Haloperidol (more), 2nd Gen Atypical Antipsychotics (less)

Question 5

which cause metabolic effects?

Answer 5

2nd Gen Atypical Antipsychotics (Olanzapine most, Ari least)

Question 6

which cause insomnia?

Answer 6

Ari (most stim of 2nd Gen), Stimulants

Question 7

which cause headaches?

Answer 7

Ari

Question 8

which cause DRESS (Drug Reaction with
Eosinophilia and Systemic
Syndrome, hypersensitivity rxn)?

Answer 8

Olanzapine

Question 9

which can cause cataracts with long-term use?

Answer 9

Quetiapine (eye exams at initiation and periodically)

Question 10

which cause weight loss?

Answer 10

Stimulants

Topiramate (can be used off-label for weight loss)

Question 11

which have cardiac effects?

Answer 11

Stimulants

Question 12

which have increased absorption with food?

Answer 12

Methylphenidate (take IR tablets 30-45 min before meals)

Question 13

which have abuse potential?

Answer 13

Stimulants (both CII)

Question 14

which can cause GI upset?

Answer 14

Antiseizures (Take with food if GI upset occurs)

Question 15

which worsen if not taken as prescribed?

Answer 15

Antiseizures

Question 16

which can cause SJS/TEN (life threatening)?

Answer 16

Lamotrigine, titrate slowly

counseling points: tell patients to report any rash or fever

Question 17

which can cause abnormal behavior?

Answer 17

Levetiracetem
counseling points: tell patients to report any unusual changes in mood/behavior
if you levitate randomly, that’s abnormal

Question 18

which have a risk of gingival hyperplasia?

Answer 18

Phenytoin

counseling points: tell patients to maintain good oral hygiene

Question 19

which can cause Hirsutism (excessive body hair)?

Answer 19

Phenytoin

counseling points: tell patients that they may grow hair on parts where it is absent/minimal

Question 20

which is a potent CYP450 inducer and has a narrow therapeutic index?

Answer 20

Phenytoin

counseling points: tell patients to report any new meds

Question 21

which can word-finding difficulty/abnormal thinking in 6% of patients?

Answer 21

Topiramate
counseling point: tell patients that they may experience memory/concentration difficulty and slow thoughts
“hold on, it’s at the top of my head”