Antibiotic Man

Question 1

CURB65 0-2

Answer 1

amoxicillin

if penicillin allergic, doxycycline

Question 2

CURB65 3-5

Answer 2

co amoxiclav + clarithromycin/doxcycline

if penicillin allergic, levofloxacin

Question 3

HAP/Aspiration pneumonia severe

Answer 3

IV amoxicillin + gentamicin + metronidazole

if penicillin allergic, IV co trimoxazole + metronidazole +/- gentamicin

Question 4

HAP/Aspiration pneumonia non severe

Answer 4

Amoxicillin and metronidazole

if penicillin allergic, Co trimoxazole + metronidazole

Question 5

acute exacerbation of COPD

Answer 5

1st amoxicillin

2nd doxycycline

Question 6

native valve endocarditis (subacute)

Answer 6

amoxicillin and gentamicin

Question 7

native valve severe sepsis, due to endocarditis (acute)

Answer 7

flucloxacillin

Question 8

prosthetic valve/suspected MRSA

Answer 8

vancomycin and rifampicin

Question 9

native valve severe sepsis + risk factors for resistant pathogens

Answer 9

vancomycin and meropenem

Question 10

C Diff infection non severe

Answer 10

metronidazole

Question 11

C Diff infection severe

Answer 11

vancomycin +/- metronidazole

Question 12

Peritonitis/biliary tract/intra abdo

Answer 12

amoxicillin + metronidazole + gentamicin

if penicillin allergic, vancomycin + metronidazole + gentamicin

Question 13

spontaneous bacterial peritonitis severe

Answer 13

piperacillin/tazobactam

Question 14

spontaneous bacterial peritonitis non severe

Answer 14

co-trimoxazole

Question 15

unknown source

Answer 15

amoxacillin + metronidazole + gentamicin

if penicillin allergic,
vancomycin + metronidazole + gentamicin