antibiotic resistance

Question 1

Resistance mechanisms: inactivation

Answer 1

destruction of an antibiotic
e.g. beta lactamases and transferases

Question 2

beta lactamases

Answer 2

cleave beta lactam ring
different bla genes that target different penecillins
such as serine beta-lactamase and metallo beta-lactamase
DOES NOT TARGET CARBAPENEMS

Question 3

transferases + example

Answer 3

aminoglycoside modifying enzymes covalently modify -OH or -NH2 groups
normally on mobile genetic elements