Antibiotics

Question 1

Beta-Lactams

Answer 1

Penicillins: Penicillin G, Aminopenicillins (Amoxicillin)
Extended spectrum penicillins (ticarcillin)

Cephalosporins

Others: carbapenem, Imipenem, Beta-lactamse inhibitors (Clavulanic acid)

Question 2

Aminoglycosides

Answer 2

Gentamycin

amikacin

Question 3

Phenicols

Answer 3

Chloramphenicol (SA)

Florphenicol (LA)

Question 4

Lincosamides

Answer 4

Lincomycin

Clindamycin

Question 5

Tetracyclines

Answer 5

Oxytetracyclin

Doxycyclin

Question 6

Fluoroquinolones

Answer 6

Enrofloxacin

Marbofloxacin

Question 7

Macrolides

Answer 7

Azithromycin

Tylosin

Question 8

Polypeptides

Answer 8

Vancomycin
Bacitracin
Polymixin

Question 9

Potentiated sulfonamides

Answer 9

sulfas + trimethoprim

Question 10

Miscellaneous antibiotics

Answer 10

Rifampin (horses)

Metronidazole

Question 11

Cell wall synthesis inhibitors

Answer 11

Penicillin (Beta lactams)
Cephalosporin (Beta lactams)
Vancomycin (polypeptide)

Question 12

Inhibition of Protein synthesis (30s or 50s)

Answer 12

Chloramphenicol
Tetracyclin
Clindamycin

Question 13

Cell Membrane Leakage

Answer 13

Polymixin
Nystatin
Amphotericin B

Question 14

Inhibition of protein synthesis (30s) aminoglycosides

Answer 14

Gentamicin

Amikacin

Question 15

Affect nucleic acid metabolism

Answer 15

Rifampin

Enrofloxacin

Question 16

Anti-metabolites

Answer 16

Trimethoprim

Sulfonamides

Question 17

Antibiotics that are concentration dependent

Answer 17

Quinolones
Aminoglycosides
Metronidazole

Question 18

Antibiotics that are time-dependent (no persistent effects)

Answer 18

Beta lactams

Question 19

Antibiotics that are time-dependent (with persistent effects)

Answer 19

Macrolides
Tetracyclines
Lincosamides

Question 20

What is the most important mechanism of antibiotics resistance?

Answer 20

Plasmid

Question 21

How to slow resistance process

Answer 21

Judicious use
Culture and sensitivity
Correct dose, frequency, and route
Avoid using the newest antibiotic

Question 22

What antibiotics target cell wall?

Answer 22

Penicillins
Cephalosporins
Carbapenems

Question 23

What antibiotics target ribosome 30s?

Answer 23

Aminoglycosides

Tetracyclines

Question 24

What antibiotics target ribosome 50s?

Answer 24

Macrolides
Phenicols
Lincosamides

Question 25

What antibiotics target purine metabolism?

Answer 25

Sulfonamides

Question 26

What antibiotics target DNA?

Answer 26

Fluoroquinolones Nitrofurans Rifampins

Question 27

Penicillins

Answer 27

Amoxicillin Penicillin G Ticarcillin

Question 28

First generation Cephalosporins

Answer 28

``` cefazolin cephalexin (dogs) ```

Question 29

Second generation cephalosporins

Answer 29

none used at uf

Question 30

Third generation cephalosporins

Answer 30

Cefotaxime | Ceftiofur (SA and LA)

Question 31

What are the major toxicities of aminoglycosides?

Answer 31

Nephrotoxicity Ototoxicity Neurotoxicity

Question 32

How do tetracyclines work?

Answer 32

Bacteriostatic - reversible inhibition of 30s

Question 33

What drug MUST be followed with water in cats?

Answer 33

Doxycycline

Question 34

What antibiotics are bacteriostatic with inhibition of 50s?

Answer 34

Phenicols Macrolides Lincosamides

Question 35

Antibiotics that penetrate CNS

Answer 35

Chloramphenicol Doxycycline Metronidazole Some 3rd gen cephalosporins