Antibiotics Drugs Flashcards
primarily effective against one type of organism
Narrow spectrum
Drug of choice: Streptococcus, meningitis, syphilis
Penicillin
Have the broadest antibacterial actions of any antibiotics; Bactericidal and inhibit cell wall synthesis and are often reserved for complicated body cavity and connective tissue infections
Carbapenems
DOC: Rickettsia, Chlamydia, Mycoplasma, Spirochetes
Tetracyclines
DOC for LEGIONNAIRES CAMP on My Border (Legionnella, Campylobacter, Mycoplasma, Bordetella)
Macrolides
Bactericidal and potent thus DOC for virulent infections through binding with 30S ribosome
AMINOGLYCOSIDES ( Amikacin, Gentamicin, Tobramycin)
Suitable for treating complicated UTIs, but can be given to patients with respiratory, skin, GIT, and bone infections; Destroy bacteria by altering DNA
Quinolones
Inhibit bacterial growth by preventing synthesis of folic acid
SULFONAMIDES AND TRIMETHOPRIM Sulfamethoxazole-Trimethoprim (SMZ-TMP)
Indicated for acute UTI and prophylaxis of recurrent UTI; broad spectrum antiseptic through damaging MOs DNA
Nitrofurantoin, nitrofurantoin macrocrystals, methenamin (Antiseptic )
a tuberculosis that demonstrates resistance to two or more drugs
Multi-drug resistant TB
binds to sterols in the cell membranes of the fungi
Polyenes
Combats rapidly growing fungi and inhibits fungal cell P450 enzymes
Imidazoles(Ketoconazole) & Triazoles ( Fluconazole, Itraconazole, Voriconazole, Posaconazole
prevents synthesis of glucans which are found in fungal cell walls
Echinocandins (Caspofungin, Micafungin, Anidulafungin)
Chloroquine and hydroxychloroquine; Mefloquine and Quinine
works by inhibiting DNA and RNA polymerase and raises the pH within the parasite which interferes with the parasite’s ability to metabolize and use erythrocyte’s hemoglobin
Destroys worm’s cytoplasm which immobilizes and kills the worm
Albendazole