Antibiotics part 2 Flashcards

Question

erythromycin indications

Answer 1

``` gastroparesis CAP (1st line) PCN-allergic AOM, strep chlamydia in newborn pertussis/diptheria rheumatic fever prophylax (DOC) ```

Answer 2

``` H. pylori/duodenal ulcer (DOC) mycobact infection (DOC for HIV) CAP PCN-allergic AOM, strep pertussis/diptheria ```

Answer 3

``` chlamydia mycobact infection (DOC for HIV) acute exacerbations of COPD CAP PCN-allergic AOM, strep pertussis/diptheria ```

Answer 4

``` long QT p450 3A4 inhibitor and substrate (clarithro and erythro) N/V/D/cramps SJS/TEN seizure interstital nephritis hearing loss dysguesia (clarithro) ```

Answer 5

telithromycin

Answer 6

50S ribosomal substrate inhibitor | bacteriocidal

Answer 7

MDR strep pneumo (esp PCN-resistant) | CAP

Answer 8

myasthenia gravis | liver problems

Answer 9

liver and kidney probs/monitor | p450 metab

Answer 10

clindamycin

Answer 11

50S ribosomal inhibitor | bacteriostatic until its cidal

Answer 12

sepsis malaria AOM/RTI/strep (PCN-allergic) SSTI and other anaerobe infections

Answer 13

``` N/V/D (will get D) c.diff rash jaundice/increase LFT leukopenia, eosinophilia (rare) ```

Answer 14

``` tetracycline minocycline doxycycline tigecycline demeclocycline ```

Answer 15

30S ribosomal inhibitor | bacteriostatic

Answer 16

``` acne animal bites/probs (lyme, vibrio, malaria, RMSF) psittacosos/ornithosis syphilis (in PCN= CI) demeclocycline: SIADH ```

Answer 17

``` photosensitivity N/V/D hyperpigmentation teeth discoloration candidiasis (doxy) black hairy tongue ```

Answer 18

``` expired meds (will pop the kidney) pregnancy/lactation (cat D) avoid with hepatic insufficiency ```

Answer 19

Al, Mg, Fe, Ca diary products anticoagulants digoxin (some)

Answer 20

ciprofloxin, ofloxin (2nd gen) | levofloxin, moxifloxin (3rd gen)

Answer 21

DNA gyrase and topoisomerase inhibitors | bacteriocidal (rapid cell death)

Answer 22

cipro: pyelonephritis, UTI | moxi/levo: lower RTI, CAP with comorbidities (1st line), HAP, pseudomonas, plague

Answer 23

``` GI: N/V/D/cramps CNA: HA, dizzy, insomnia, delirium CV: torsades, long QT neuro: polyneuropathy BGL probs (up and down) ```

Answer 24

peds | cipro: p450 probs

Answer 25

Al, Mg, Fe, Ca

Answer 26

sulfacetamide silver sulfadiazine sulfasalazine sulfamethoxazole-trimethoprim

Answer 27

PABA analog-- prevents synthesis of folate b/c bact picks up sulfa drug instead of PABA bacteriosatic

Answer 28

``` uncomplicated UTI toxoplasmosis PCP pneumonia travelers diarrhea AOM shigellosis MRSA cellulitis ```

Answer 29

prevention of bacterial infection of a burn (not tx!)

Answer 30

bacterial conjunctivitis

Answer 31

ulceritive colitis

Answer 32

MRSA cellulitis UTI acute exacerbation of chronic bronchitis

Answer 33

``` GI photosensitivity bone marrow suppression (with radiation) hemolytic anemia SJS/TEN (rare) meningitis ```

Answer 34

``` gentamycin amikasin tobramycin neomycin streptomycin ```

Answer 35

30S subunit inhibitor | bacteriocidal

Answer 36

pregnancy folate deficiency newborn

Answer 37

``` cyclosporine (decrease [x]) can block some ABX effects phenytoin sulfonylureas warfarin (increase effect) ACEI/ARB: affect K+ ```

Answer 38

``` pyelonephritis severe UTI with resistant org opthalmic/otic infect HAP with MDR (tobra if CF too) sepsis with pseudomonas ```

Answer 39

ototoxicity (neo, amik, tobra) ataxia/vertigo (strep, gent, tobr) tinnitus (first sign of ototox --> BAD) nephrotoxicity (mainly neo)

Answer 40

obese ppl: doesnt distrib well in periphery

Answer 41

fosfomycin nitrofurantoin phenazopyradine

Answer 42

inhib cell wall synthesis | bacteriocidal

Answer 43

UTI (uncomplic-- E facelis and E coli)

Answer 44

``` c. diff N/D HA vaginitis rhinitis ```

Answer 45

goes intracellular: disturb RNA/DNA | bacteriocidal

Answer 46

UTI (uncomplic--E facelis, E coli) | good to use if preg

Answer 47

N/V/D chronic hepatitis (rare) IPF (long term use- rare) neuro manifestations

Answer 48

NOT AN ABX!

Answer 49

analgesic during UTI (decrease burn, itch, frequency, urgency)

Answer 50

turns urine orange

Answer 51

``` vancomycin oxazoladinones lipoglycopeptides mupirocin quinipristin-dalfopristin colistin ```

Answer 52

inhib cell wall synthesis | bacteriocidal

Answer 53

``` MRSA pneumonia septicemia c. diff bone/joint infections ```

Answer 54

it's a non-selective MAOI, so no deli meats, cheese, beer, wine, etc

Answer 55

``` red-man flush phlebitis renal toxicity rash (rare) ototoxicity (rare) ```

Answer 56

linezolid | tedizolid

Answer 57

50S subunit inhibitor | bacteriostatic and cidal (depend on org)

Answer 58

``` MRSA VRSA VRE strep (PCN-resist) SSTI (with resist bact) ```

Answer 59

SSTI | MRSA

Answer 60

oritavancin | dalbavancin

Answer 61

inhib bact cell wall cross-linking

Answer 62

MRSA | SSTI (cellulitis, wound infect, abscess)

Answer 63

GI: N/V/D pancytopenia HA lactic acidosis

Answer 64

``` SSRIs TCA tramadol dextromethorphan Epi/NE/DA ```

Answer 65

``` infusion rxn c. diff osteomyelitis neutropenia N/V/ HA dizzy worsen abscess ```

Answer 66

warfarin/heparin (increase effect)

Answer 67

``` c. diff infusion rxn elevated LFTs N/D HA ```

Answer 68

inhib protein synthesis

Answer 69

colonization of MRSA in the nose | impetigo (SSTI)

Answer 70

``` sting, itch, irritate tingle, burn sore facial pn post nasal drip sinusitis rhinitis conunctivitis ```

Answer 71

steogramin ABX inhib prot synthesis bacteriocidal

Answer 72

VRE life-threat | really bad SSTI

Answer 73

arthalgias/myalgias hyperbiluribinemia c. diff

Answer 74

increase membrane permeability | neutralize endotoxins

Answer 75

last line defense for MRSA