Anticholinergic Drugs

Question 1

What is the Trade name of atropine?

Answer 1

Atropen

Question 2

Describe: 💊atropine

Direct/Indirect, MOA, Indications,Therapeutic Effects, Side Effects, Contraindications, Nursing Implications (Monitor)

Answer 2

Direct/Indirect

• Direct

MOA

• Binds to muscarinic receptors -> prevent ACh from binding/activating -> ↓parasympathetic effect

Indications

• Cholinergic (anticholinesterase) toxicity
• Bradycardia
• Opthamalic examinations

Therapeutic Effects

↑Sympathetic actions:
* ↑ heart rate
* Dilates pupils

Side Effects

• Tachycardia
• Blurred vision
• ↑intraocular pressure
• Constipation
• Urinary retention

Contraindications

• Glaucoma
• BPH

Nursing Implications
Monitor

• VS
• I&Os

Question 3

What is the Trade name for ipratropium?

Answer 3

Atrovent HFA

Question 4

Describe: ipratropium

Direct/Indirect, MOA, Route, Indications,Therapeutic Effects, Side Effects, Contraindications, Nursing Implications (Assess)

Answer 4

Dry mouth Direct/Indirect

• Direct

MOA

• Binds to muscarinic receptors -> prevent ACh from binding/activating -> ↓parasympathetic effect

Route

• Inhaler

Indications

• Asthma
• COPD

Therapeutic Effects

↑Sympathetic actions:

• Bronchodilation
• Drying/decrease secretions
  -> Ex: Patient with peptic ulcer disease have ↑HCl -> give anticholinergic -> decrease acid secretion

Side Effects

• Dry mouth

Contraindications

• Glaucoma
• BPH

Nursing Implications
Assess
* Breath sounds