Anticonvulsants TBL Flashcards Preview

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Flashcards in Anticonvulsants TBL Deck (10):
1

Carbamezepine

1st line Tx for focal seizures (w/ or w/o 2ndary generalized seizures). Also a mood stabilizer. Note p450 inducer- many interactions.

2

Phenytoin

high efficacy for focal seizures. P450 inducer.

3

Gabapentin

a less good choice for focal seizures. Better interaction profile than carbamezapine or phenytoin.

4

Valproate

most effective treatment for generalized seizures.

5

Ethosuximide

best Tx for absence seizures

6

What proportion of patients will have sustained remission with initial therapy and no severe side effects?

50%

7

If pt is having bad side effects or continues to have seizures, what do you do?

Make sure they're taking it first. If they are, then switch to a different first line drug.

8

When is a pt considered truly pharmacoresistant?

If they fail 2 first line meds, either alone or in combo

9

When is it ok to discontinue therapy for epilepsy?

2-4 years seizure-free.

10

What's the number 1 reason for non-adherence?

forgot! Physicians and patients agree on this.