ANTIDEPRESSANTS Flashcards
Classifications of Antidepressants
SSRIs - Selective Seroton reuptake inhibitor)
SNRI/DNRI - Serotonin norepinephrine/ Dopaminr Norepinephrine Reuptake Inhibitor
TCA - Tricyclic Antidepressants
MAOI’s - Monoamine axidase inhibitor
SSRI mode of action
Inhibits UPTAKE OF SEROTONIN (Increased serotonin)
Uses of SSRI (4)
Depression, anxiety, OCD, Eating disorder
Side effects of SSRI in neuro
Headache, tremors, difficulty sleeping
Side effects of SSRI in GI
Nausea, dry mouth, thirst, constipation, urinary retention, sexual dysfunction
3s of SSRI
SEROTONIN Syndrome
SEXUAL Dysfunction
Stomach Issues
Too much serotonin in brain is called?
Serotonin syndrome
Descriptions for serotonin syndrome (6)
- too much serotonin in brain
- mental changes
- tachycardia
- tightness in muscle
- difficulty walking
- increase temp and bp
How SSRIs are administered to px?
Administered with meals
How many weeks gap should SSRI be administered before giving MAOIs and TCA?
5 weeks
After giving TCA/MAOIs, after how many weeks will it take before givimg SSRI?
2 weeks
How many weeks for SSRI to take and effect?
4-6 weeks
When should SSRIs be taken?
In the morning
SSRIs is the?
First line drug for anxiety and depression
What should we educate to px taking SSRIs?
Importance of compliance
What will happen to px with suicid plans?
Have the energy due to meds to carry out plan
Generic drugs for SSRI (5)
Sertraline
Citalopram
Escitalopram
Fluoxetine
Vilazodone
Trade name for sertraline
Zoloft
Trade name fir citalopram
Celexa
Trade name for escilatopram
Lexapro
Trade name for fluoxetine
Prozac
Trade name for Vilazodonr
Vibryd
Suffixes used in SSRIs (3)
- talopram
- oxetine
-zodone
It affects serotonin norepinephrine and dopamin (classification of antidepressants)
SNRI/DNRI
