Antidepressants Flashcards
(24 cards)
TCA MOA?
Inhibit uptake: NE, 5HT
Block M, alpha, histamine receptors
TCA drug names? (4)
Amitriptyline
Imipramine
Nortriptyline
Desipramine
TCA common s/e? (7)
Sedation Tachy/palp Ortho hypoTN Constipation Urinary retention Weight gain Sex dysfxn
TCA bad s/e? (4)
Seizures
SIADH (hypoNa+)
Torsades in OD
Serotonin synd
TCA uses? (3)
Depression
Panic
Chronic pain/Fibro
SSRI drug names? (5)
Fluoxetine/Prozac Paroxetine/Paxil Sertraline/Zoloft Citalopram/Celexa Escitalopram/Lexapro
SSRI uses?
Depression (class is DOC) Panic OCD (Paxil DOC) Social anxiety (Paxil DOC) Bulimia EtOH
SSRI s/e? (5)
N/D/C Anxiety Insomnia (flu, ser) Sedation (pax) Sex dysfxn
SSRI bad s/e? (3)
Serotonin synd (esp MAOI, St John's) Drug interactions (anticonvulsants, warfarin, b-block) SIADH
SNRI drug names? (3)
Venlafaxine/Effexor
Duloxetine/Cymbalta
Desvenlafaxine/Pristiq
SNRI uses? (5)
Depression Panic/GAD/PTSD DM neuro pain Fibro Hot flashes
SNRI s/e? (5)
Same as SSRI Anorexia Sweating Dizziness HTN
Duloxetine/Cymbalta contraindicated for who?
Narrow-angle glaucoma
Best SSRI for EtOHics?
Paxil (withstands reduced effectiveness caused by EtOH)
Bupropion MOA?
Inhib DA/NE re-uptake
Bupropion uses? (4)
Depression
Smoking cess
EtOHism
+SSRI to dec sex dysfxn
Bupropion s/e? (3)
Wgt loss
Anxiety
Insomnia
Bupropion bad s/e?
Seizures
Don’t use with antipsych or TCA
Mirtazapine/Remeron MOA?
Inc release NE/5HT
Mirtazapine benefits?
NO SSRI s/e Anxiety Insomnia Sex dysfxn
Mirtazapine s/e? (4)
Drowsiness
Dizziness
HA
Wgt gain
Trazodone/Desyrel MOA?
5HT receptor antagonist
Trazodone uses? (3)
Insomnia
Depression
Combatives
Trazodone s/e? (3)
Ortho hypoTN
Dry mouth
N
